Autoimmune polyglandular syndrome type 3 complicated by mineralocorticoid-responsive hyponatremia of the elderly  

作　　者：Hidekatsu Yanai Seiko Okamoto Junwa Kunimatsu 

机构地区：[1]Department of Internal Medicine,Kohnodai Hospital,National Center for Global Health and Medicine

出　　处：《World Journal of Diabetes》2010年第4期135-136,共2页世界糖尿病杂志（英文版）（电子版）

摘　　要：We experienced the first case with autoimmune polyglandular syndrome type 3(anti-thyroid peroxidase ant ib ody-positive hypothyroidism and anti-glutamic acid decar boxylase antibody-positive diabetes) complicated by miner alocorticoid-responsive hyponatremia of the elderly.This case is also a rare slowly progressive insulin-dependent diabetes mellitus(SPIDDM) case,for which the patient has been treated for many years with sulfonylurea or glinide.Our observation also demonstrated that glucose metabolism in autoimmune diabetes such as SPIDDM is influenced by appetite,thyroid function and glucocorticoid effect.We experienced the first case with autoimmune polyglandular syndrome type 3 (anti-thyroid peroxidase antibody-positive hypothyroidism and anti-glutamic acid decarboxylase antibody-positive diabetes) complicated by mineralocorticoid-responsive hyponatremia of the elderly. This case is also a rare slowly progressive insulin-dependent diabetes mellitus (SPIDDM) case, for which the patient has been treated for many years with sulfonylurea or glinide. Our observation also demonstrated that glucose metabolism in autoimmune diabetes such as SPIDDM is influenced by appetite, thyroid function and glucocorticoid effect.

关 键 词：Anti-glutamic acid DECARBOXYLASE antibody AUTOIMMUNE polyglandular syndrome Mineralocorticoidresponsive HYPONATREMIA of the elderly Slowly progressive INSULIN-DEPENDENT diabetes MELLITUS 

分 类 号：R587.1[医药卫生—内分泌]