Diagnosis and management of Barrett’s metaplasia:What’s new?  

作　　者：Fábio Segal Helenice Pankowski Breyer 

机构地区：[1]Physician and Endoscopist at Hospital Moinhos de Vento,Porto Alegre-RS,90.035-001,Brazil [2]Physician and Endoscopist at Hospital de Clínicas,Porto Alegre-RS,90.035-003,Brazil

出　　处：《World Journal of Gastrointestinal Endoscopy》2012年第9期379-386,共8页世界胃肠内镜杂志（英文版）（电子版）

摘　　要： Barrett’s esophagus(BE) is a complication of gastroesophageal reflux disease,and a premalignant lesion for esophageal adenocarcinoma(EAC).Observational studies suggest that endoscopic surveillance is associated with the detection of dysplasia and EAC at an early stage along with improved survival,but controversies still remain.The management of patients with BE involves endoscopic surveillance,preventive and clinical measures for cancer,and endoscopic and surgical approaches to treatment.Deciding upon the most appropriate treatment is a challenge.This study presents the results and the effectiveness of these practices.Barrett’s esophagus (BE) is a complication of gastroesophageal reflux disease, and a premalignant lesion for esophageal adenocarcinoma (EAC). Observational studies suggest that endoscopic surveillance is associated with the detection of dysplasia and EAC at an early stage along with improved survival, but controversies still remain. The management of patients with BE involves endoscopic surveillance, preventive and clinical measures for cancer, and endoscopic and surgical approaches to treatment. Deciding upon the most appropriate treatment is a challenge. This study presents the results and the effectiveness of these practices.

关 键 词：Barrett’s esophagus Intestinal METAPLASIA METAPLASTIC COLUMNAR MUCOSA ESOPHAGEAL PREMALIGNANCY ESOPHAGEAL adenocarcinoma 

分 类 号：R735.1[医药卫生—肿瘤] R571[医药卫生—临床医学]