METAPLASIA

作品数：116被引量：489H指数：12
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相关领域：医药卫生更多>>
相关作者：吴煜尤江云更多>>
相关机构：中国中医研究院更多>>
相关期刊：《Journal of Pancreatology》《Chinese Journal of Integrative Medicine》《World Journal of Gastroenterology》《World Journal of Gastrointestinal Pharmacology and Therapeutics》更多>>
相关基金：国家自然科学基金浙江省卫生厅资助项目国家教育部博士点基金重庆市自然科学基金更多>>
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Relationship between gastric mucosal atrophy by endoscopy and non-ampullary duodenal epithelial tumors
《World Journal of Gastrointestinal Oncology》2025年第2期84-92,共9页Kazuya Ohno Eiji Nakatani Takafumi Kurokami Asami Kawai Ryosuke Itai Masanori Matsuda Yuichi Masui Tatsunori Satoh Shinya Ikeda Taiyo Hirata Shodai Takeda Makoto Suzuki Ken Haruma 
BACKGROUND The pathogenesis of non-ampullary duodenal epithelial tumors(NADETs)is not fully understood.NADETs that express gastric-type mucin phenotypes(GNADETs)are noteworthy because of their high malignancy.Gastric ...
关键词：Gastric acidity Gastric foveolar metaplasia Gastric mucosal atrophy Helicobacter pylori Mucin phenotype Nonampullary duodenal epithelial tumor 
ATN-161 alleviates caerulein-induced pancreatitis
《Journal of Genetics and Genomics》2024年第12期1447-1458,共12页Rong-rong Gao Lan-yue Ma Jian-wei Chen Yu-xiang Wang Yu-yan Li Zi-yuan Zhou Zhao-hua Deng Jing Zhong Ya-hai Shu Yang Liu Qi Chen 
supported by the National Key R&D Program of China(2022YFA1103200);the Fundamental Research Funds for the Central Universities(2024ZYGXZR077);National Natural Science Foundation of China(32270866,32300693,32471155,3247086822107045);Guangzhou basic and applied basic research funding(2024A04J6259);The Pearl River Talent Recruitment Program(2023ZT10Y154,2021ZT09Y233,2023QN10Y147);South China University of Technology(D6241240);Talent Program and Basic Research Project of Guangzhou Institutes of Biomedicine and Health,Chinese Academy of Sciences(1103792101,GIBHBRP23-02,GIBHBRP24-01);Cooperation Fund of CHCAMS and SZCH(E010221005,CFA202201006);Guangdong Provincial Key Laboratory of Stem Cell and Regenerative Medicine,Guangdong-Hong Kong Joint Laboratory for Stem Cell and Regenerative Medicine,Guangzhou Institutes of Biomedicine and Health,Chinese Academy of Sciences(KLRB202201,KLRB202305);partially supported by Science and Technology Planning Project of Guangdong Province,China(2023B1212060050,2023B1212120009)。
Pancreatitis is a common gastrointestinal disorder that causes hospitalization with significant morbidity and mortality.The mechanistic pathophysiology of pancreatitis is complicated,limiting the discovery of pharmaco...
关键词：PANCREATITIS ANGIOGENESIS ATN-161 Ductal-endothelial crosstalk Acinar-to-ductal metaplasia 
Papillary thyroid carcinoma with nodular fasciitis-like stroma-an unusual variant with distinctive histopathology:A case report
《World Journal of Clinical Cases》2023年第24期5797-5803,共7页Jun Hu Fei Wang Wei Xue Yong Jiang 
BACKGROUND Papillary thyroid carcinoma(PTC)is regarded as a fairly common endocrine malignancy,which can be divided into different multiple variants due to wide morphologic differences.The majority of PTC variants hav...
关键词：Papillary thyroid carcinoma Nodular fasciitis-like stroma Spindle cell METAPLASIA Neck ultrasound Differential diagnosis Case report 
Helicobacter pylori plays a key role in gastric adenocarcinoma induced by spasmolytic polypeptide-expressing metaplasia被引量：3
《World Journal of Clinical Cases》2023年第16期3714-3724,共11页Mian-Li Li Xin-Xin Hong Wei-Jian Zhang Yi-Zhong Liang Tian-Tian Cai Yi-Fei Xu Hua-Feng Pan Jian-Yuan Kang Shao-Ju Guo Hai-Wen Li 
Supported by the Guangdong Basic and Applied Basic Research Foundation,No.2020A1515110947;the National Natural Science Foundation of China,No.82104747;the Scientific Research Project of Guangdong Bureau of Traditional Chinese Medicine,No.20231303;the Guangdong Provincial Key Research and Development Plan,No.2020B1111100011.
Heliobacter pylori(H. pylori), a group 1 human gastric carcinogen, is significantly associated with chronic gastritis, gastric mucosal atrophy, and gastric cancer.Approximately 20% of patients infected with H. pylori ...
关键词：Gastric cancers Helicobacter pylori Intestinal metaplasia Macrophages Spasmolytic polypeptide-expressing metaplasia 
MG7-Ag, hTERT, and TFF2 identified high-risk intestinal metaplasia and constituted a prediction model for gastric cancer被引量：4
《Chinese Medical Journal》2023年第5期610-612,共3页Siran Wu Xiaodong Qu Na Wang Luyao Zhang Xingyu Zhao Qiong Wu Junye Liu Yongquan Shi 
Shaanxi Foundation for Innovation Team of Science and Technology(No.2018TD-003);Project from State Key Laboratory of Cancer Biology(No.CBSKL2019ZZ07)
To the Editor:Gastric cancer(GC)ranks third in incidence and mortality both worldwide and in China.[1,2]Intestinal metaplasia(IM)significantly increases risk of GC so that identifying high-risk IM patients who will pr...
关键词：TFF2 METAPLASIA Gastric 
Endoscopic characteristics in predicting prognosis of biopsy-diagnosed gastric low-grade intraepithelial neoplasia被引量：6
《Chinese Medical Journal》2022年第1期26-35,共10页Long Zou Qingwei Jiang Tao Guo Xi Wu Qiang Wang Yunlu Feng Shengyu Zhang Weigang Fang Weixun Zhou Aiming Yang 
This work was supported by grants from the Beijing Municipal Science and Technology Program(No.Z181100001618013);the National Key Research and Development Program of China(No.2016YFC1302802)。
Background: Endoscopic biopsy can underestimate gastric malignancies as low-grade intraepithelial neoplasia (LGIN). Definitively diagnosed LGIN would progress. This study aimed to evaluate predictive factors to identi...
关键词：Diagnostic errors Disease progression ENDOSCOPY METAPLASIA Stomach neoplasms 
Pyloric-gland metaplasia may be an origin of cancer and intestinal metaplasia with possible CDX2 expression
《Gastroenterology Report》2021年第4期370-373,I0003,共5页Kazuyoshi Yagi Atsunori Tsuchiya Satoru Hashimoto Taisuke Kato Osamu Onodera Shuji Terai 
supported by a Grant-in-Aid for Scientific Research(C)[19K08389]from the Ministry of Education,Culture,Sports,Science and Technology of Japan.
Introduction The majority of cases of gastric cancer are thought to develop due to chronic inflammation from Helicobacter pylori(H.pylori)infection leading to intestinal metaplasia,termed the intestinal metaplasia–dy...
关键词：肠上皮化生 幽门腺 HELICOBACTER CDX2 
Is intestinal metaplasia the point of no return in the progression of gastric carcinogenesis?被引量：1
《Chinese Medical Journal》2021年第24期2965-2967,共3页Si-Ran Wu Yu-Hao Liu Yong-Quan Shi 
supported by grants from Shaanxi Foundation for Innovation Team of Science and Technology(No.2018TD-003);Project from State Key Laboratory of Cancer Biology(No.CBSKL2019ZZ07)。
Gastric cancer(GC)is one of the most common malignant tumors worldwide.In China,GC is the second most common malignant tumor,and it is the second leading cause of cancer mortality.[1]Correa model showed that the devel...
关键词：GASTRITIS GASTRIC METAPLASIA 
Preventive and inhibitive effects of Yiwei Xiaoyu granules on the development and progression of spasmolytic polypeptideexpressing metaplasia lesions被引量：9
《World Journal of Gastrointestinal Oncology》2021年第11期1741-1754,共14页Wan-Qun Chen Feng-Liang Tian Jin-Wei Zhang Xiao-Jun Yang Yan-Ping Li 
Supported by National Natural Science Foundation of China,No.81904175;Natural Science Foundation of Chongqing,China,No.cstc2018jcyjAX0756;Chongqing Health Planning Commission Project,No.ZY201802063 and No.2019ZY013111.
BACKGROUND Spasmolytic polypeptide-expressing metaplasia(SPEM)is a potential preneoplastic lesion.AIM To elucidate the microRNA(miR)-7-mediated preventive and inhibitive effects of Yiwei Xiaoyu granules(YWXY)in SPEM l...
关键词：Spasmolytic polypeptide-expressing metaplasia Yiwei Xiaoyu Granules MicroRNA-7 Chronic atrophic gastritis Trefoil factor 2 Gastric precancerous lesions 
Skeletal muscle metastasis with bone metaplasia from colon cancer:A case report and review of the literature被引量：1
《World Journal of Clinical Cases》2021年第30期9285-9294,共10页Yu Guo Shuang Wang Ze-Yun Zhao Jian-Nan Li An Shang Dong-Lin Li Min Wang 
Supported by the Science and Technology Development Project of Jilin Province,No.3D5197434429;the Youth Program of the National Natural Science Foundation of China,No.3A4205367429;the Education Project of Jilin University;No.419070600046。
BACKGROUND Colon cancer is a common malignant disease of the gastrointestinal tract and usually occurs at the junction of the rectum and sigmoid colon.Lymphatic and hematogenous metastases occur frequently in colon ca...
关键词：Soft tissue metastasis Skeletal muscle metastasis OSSIFICATION Colon cancer BRAF mutation Tumor mutation burden Case report 
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