Esophagitis dissecans superficialis and autoimmune bullous dermatoses: A review  

作　　者：Akira Hokama Yu-ichi Yamamoto Kiyohito Taira Mitsuteru Nakamura Chiharu Kobashigawa Manabu Nakamoto Tetsuo Hirata Nagisa Kinjo Fukunori Kinjo Kenzo Takahashi Jiro Fujita 

机构地区：[1]Department of Infectious,Respiratory and Digestive Medicine,Faculty of Medicine, University of the Ryukyus,Okinawa 903-0125,Japan [2]Department of Dermatology,Faculty of Medicine,University of the Ryukyus,Okinawa 903-0125,Japan [3]Department of Endoscopy, University Hospital of the Ryukyus,Okinawa 903-0125,Japan

出　　处：《World Journal of Gastrointestinal Endoscopy》2010年第7期252-256,共5页世界胃肠内镜杂志（英文版）（电子版）

摘　　要：Esophagitis dissecans superficialis(EDS)is a rare and severe endoscopic finding characterized by sloughing of large fragments of esophageal mucosal lining.Although EDS has been reported in association with serious illnesses and certain medications,the pathophysiological association of autoimmune bullous dermatoses with EDS has gained remarkable attention.Among these dermatoses,pemphigus vulgaris and pemphigoid frequently present with various types of esophageal involvement including EDS.We review the pathophysiology and clinical features of this involvement with the presentation of our experiences.The importance of endoscopic evaluation of this entity is discussed.Esophagitis dissecans superficialis (EDS) is a rare and severe endoscopic finding characterized by sloughing of large fragments of esophageal mucosal lining. Although EDS has been reported in association with serious illnesses and certain medications, the pathophysiological association of autoimmune bullous dermatoses with EDS has gained remarkable attention. Among these dermatoses, pemphigus vulgaris and pemphigoid frequently present with various types of esophageal involvement including EDS. We review the pathophysiology and clinical features of this involvement with the presentation of our experiences. The importance of endoscopic evaluation of this entity is discussed.

关 键 词：ESOPHAGITIS dissecans superficialis Endoscopy AUTOIMMUNE BULLOUS DERMATOSES Pemphigus vulgaris Mucous membrane PEMPHIGOID BULLOUS PEMPHIGOID DESMOGLEIN 

分 类 号：R758.6[医药卫生—皮肤病学与性病学] R571[医药卫生—临床医学]