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supported by Open Project of Fujian Provincial Key Laboratory(Nos.XHZDSYS202004 and XHZDSYS202005);Starting Package of Xiang'an Hospital of Xiamen University(No.PM201809170010).
Introduction:Pilomatricoma is usually a solitary,deep dermal firm nodule with an overlying normal epidermis.Bullous pilomatricoma is rarely reported;thus,its pathogenesis has not been elucidated.We report a case prese...
Supported by Guiding Project of Changshu Health Committee,No.CSWZD202021;Project of the Affiliated Changshu Hospital of Xuzhou Medical University,No.CSEY202125。
BACKGROUND Diffuse retinal pigment epitheliopathy(DRPE)associated with bullous retinal detachment is a severe variant of DRPE that is frequently misdiagnosed and often improperly treated.CASE SUMMARY A 36-year-old fem...
The development of immune checkpoint inhibitors,such as those targeting programmed cell death protein 1(PD-1),represents a major breakthrough in cancer therapy.Although immune checkpoint blockade therapy has a favorab...
supported by a grant from the National Nature Science Foundation of China(No.81402588).
To the Editor:Prurigo pigmentosa is a rare inflammatory dermatosis first reported in Japan in 1971.Typical lesions of prurigo pigmentosa are erythematous papules with a reticular arrangement that quickly resolve leavi...
Cutaneous manifestations are variable in patients with eosinophilic granulomatosis with polyangiitis(EGPA).We report a case where bullous eruption was a presenting manifestation of EGPA.A 55-year-old Chinese man with ...
BACKGROUND Sweet’s syndrome,also known as acute febrile neutrophilic dermatosis,is a rare skin disorder that may be associated with cancer.CASE SUMMARY A 58-year-old female presented with a cholestatic syndrome and s...
Objective:To investigate the expression and significance of matrix metalloproteinase-2(MMP-2)and matrix metalloproteinase-13(MMP-13)in bullous pemphigoid(BP)skin lesions.Methods:Immunohistochemical SP method was used ...
Objective:To investigate the clinical efficacy of plasma exchange therapy for autoimmune bullous skin disease.Methods:Fifty patients with autoimmune bullous skin disease enrolled in our hospital from January 2018 to J...
Myringitis can be acute or chronic. Though they commonly present with ear discharge with or without pain, the etiology and the management principles differ. Granular myringitis generally is an external ear pathology e...
Bullous epidermal necrolysis drug eruption is mainly caused by drug allergy, also known as toxic epidermal necrolysis, TEN, first reported by Lyell A in 1956, also known as Lyell syndrome, is the most serious type of ...