Oxaliplatin induced disseminated intravascular coagulation: A case report and review of literature  

作　　者：Shweta Kurian Jessica Macintyre Muzammil Mushtaq Caio Max Rocha-Lima Yeon Ahn 

机构地区：[1]Division of Hematology Oncology, Sylvester Comprehensive Cancer Center, University of Miami, Miami, FL 33136, United States

出　　处：《World Journal of Gastrointestinal Oncology》2012年第7期181-183,共3页世界胃肠肿瘤学杂志（英文版）（电子版）

摘　　要：Oxaliplatin in combination with a fluoropyrimide is a treatment option for colorectal cancer patients in the adjuvant and metastatic settings. Very few hematological emergencies have been reported associated with Oxaliplatin. These include autoimmune hemolytic anemia, thrombocytopenia and pancytopenia. We present a case report of a patient who developed hematuria and disseminated intravascular coagulation while receiving the second cycle of FOLFOX and bevacizumab for metastatic colon cancer.Oxaliplatin in combination with a fluoropyrimide is a treatment option for colorectal cancer patients in the adjuvant and metastatic settings. Very few hematological emergencies have been reported associated with Oxaliplatin. These include autoimmune hemolytic anemia, thrombocytopenia and pancytopenia. We present a case report of a patient who developed hematuria and disseminated intravascular coagulation while receiving the second cycle of FOLFOX and bevacizumab for metastatic colon cancer.

关 键 词：OXALIPLATIN DISSEMINATED INTRAVASCULAR coagulation HEMATOLOGICAL EMERGENCIES METASTATIC colon cancer Platelet count 

分 类 号：R735.3[医药卫生—肿瘤]