Primary hepatic benign schwannoma  

作　　者：Michihiro Hayashi Atsushi Takeshita Kazuhiro Yamamoto Nobuhiko Tanigawa 

机构地区：[1]Department of General and Gastroenterological Surgery,Department of Pathology, Department of Radiology,Osaka Medical College Hospital [2]Department of Pathology,Osaka Medical College Hospital [3]Department of Radiology,Osaka Medi- cal College Hospital

出　　处：《World Journal of Gastrointestinal Surgery》2012年第3期73-78,共6页世界胃肠外科杂志（英文版）（电子版）

摘　　要：Schwannoma is predominantly a benign neoplasm of the Schwann cells in the neural sheath of the peripheral nerves.Occurrence of schwannoma in parenchymatous organs,such as liver,is extremely rare.A 64-year-old man without neurofibromatosis was observed to have a space-occupying lesion of 23mm diameter in the liver during follow-up examination for a previously resected gastrointestinal stromal tumor(GIST)in the small intestine.He underwent lateral segmentectomy of the liver under a provisional diagnosis of hepatic metastatic recurrence of the GIST.Histological examination confirmed the diagnosis of a benign schwannoma,confirmed by characteristic pathological findings and positive immunoreactions with the neurogenic marker S-100 protein,but negative for c-kit,or CD34.The tumor was the smallest among the reported cases.When the primary hepatic schwannoma is small in size,preopera- tive clinical diagnosis is difficult.Therefore,this disease should be listed as differential diagnosis for liver tumor with clinically benign characteristics.Schwannoma is predominantly a benign neoplasm of the Schwann cells in the neural sheath of the peripheral nerves. Occurrence of schwannoma in parenchymatous organs, such as liver, is extremely rare. A 64-year-old man without neurofibromatosis was observed to have a space-occupying lesion of 23mm diameter in the liver during follow-up examination for a previously resected gastrointestinal stromal tumor (GIST) in the small intestine. He underwent lateral segmentectomy of the liver under a provisional diagnosis of hepatic metastatic recurrence of the GIST. Histological examination confirmed the diagnosis of a benign schwannoma, confirmed by characteristic pathological findings and positive immunoreactions with the neurogenic marker S-100 protein, but negative for c-kit, or CD34. The tumor was the smallest among the reported cases. When the primary hepatic schwannoma is small in size, preoperative clinical diagnosis is difficult. Therefore, this disease should be listed as differential diagnosis for liver tumor with clinically benign characteristics.

关 键 词：LIVER SCHWANNOMA BENIGN LIVER TUMOR 

分 类 号：R739.4[医药卫生—肿瘤]