Gastroesophageal reflux disease and the airway-essentials for the surgeon  

作　　者：Vic Velanovich 

机构地区：[1]Division of General Surgery,Henry Ford Hospital,Detroit

出　　处：《World Journal of Gastrointestinal Surgery》2009年第1期8-10,共3页世界胃肠外科杂志（英文版）（电子版）

摘　　要：Gastroesophageal reflux disease(GERD) has many protean manifestations.Some of the most vexing have to do with the airway.GERD affects the tracheobronchial tree directly,leading to aspiration pneumonia and asthma,or exacerbating existing pulmonary disease,such as asthma or chronic obstructive pulmonary disease.In addition to the respiratory manifestation of GERD,there are unique pharyngeal and laryngeal manifestations.These include voice hoarseness,throat-clearing,chronic cough,globus,and "post-nasal drip".Linking these symptoms to GERD is challenging and frequently the diagnosis is that of exclusion.Despite proton pump inhibitor therapy being the mainstay of treatment,with anti-reflux surgery being reserved for intractable cases,there is no definitive evidence of the superiority of either.Gastroesophageal reflux disease (GERD) has many protean manifestations. Some of the most vexing have to do with the airway. GERD affects the tracheobronchial tree directly, leading to aspiration pneumonia and asthma, or exacerbating existing pulmonary disease, such as asthma or chronic obstructive pulmonary disease. In addition to the respiratory manifestation of GERD, there are unique pharyngeal and laryngeal manifestations. These include voice hoarseness, throat-clearing, chronic cough, globus, and “ post-nasal drip” . Linking these symptoms to GERD is challenging and frequently the diagnosis is that of exclusion. Despite proton pump inhibitor therapy being the mainstay of treatment, with anti-reflux surgery being reserved for intractable cases, there is no definitive evidence of the superiority of either.

关 键 词：GASTROESOPHAGEAL REFLUX DISEASE Laryngo-pharyngeal REFLUX Reflux-induced asthma Aspiration pneumonia CHRONIC obstructive pulmonary DISEASE CHRONIC cough REFLUX LARYNGITIS 

分 类 号：R655.4[医药卫生—外科学]