Bilateral primary xanthoma of the humeri with pathologic fractures: A case report  

作　　者：Sayed Ali Alex Fedenko Ali B Syed George Matcuk Dakshesh Patel Chris Gottsegen Eric White 

机构地区：Department of Radiology,Temple University Hospital Department of Pathology, University of Southern California, Keck School of Medicine Department of Radiology, University of Southern California, Keck School of Medicine

出　　处：《World Journal of Radiology》2013年第9期345-348,共4页世界放射学杂志（英文版）（电子版）

摘　　要： Xanthomas are rare bone tumors that occur more often in the appendicular skeleton and typically appear radiographically benign,with a narrow zone of transition and a sclerotic rim.We report the case of a 57-year-old woman with hyperlipidemia presenting with bilateral shoulder pain after minor trauma.Radiographic and histopathologic investigation demonstrated intraosseous xanthoma with atypical features,including multifocality,a wide zone of transition and pathologic fractures-characteristics more commonly associated with aggressive lesions such as multiple myeloma or metastasis.The diagnosis,imaging,and histological appearance of xanthoma of bone are reviewed.Xanthomas are rare bone tumors that occur more often in the appendicular skeleton and typically appear radiographically benign,with a narrow zone of transition and a sclerotic rim.We report the case of a 57-year-old woman with hyperlipidemia presenting with bilateral shoulder pain after minor trauma.Radiographic and histopathologic investigation demonstrated intraosseous xanthoma with atypical features,including multifocality,a wide zone of transition and pathologic fractures-characteristics more commonly associated with aggressive lesions such as multiple myeloma or metastasis.The diagnosis,imaging,and histological appearance of xanthoma of bone are reviewed.

关 键 词：XANTHOMA HYPERLIPIDEMIA PATHOLOGIC FRACTURE 

分 类 号：R738[医药卫生—肿瘤]