Pharmacological and biomedical properties of sea anemones Paracondactylis indicus,Paracondactylis sinensis,Heteractis magnifica and Stichodactyla haddoni from East coast of India  

作　　者：Bragadeeswaran Subramanian Thangaraj Sangappellai Rajiv Chandra Rajak Balaji Diraviam 

机构地区：[1]Centre of Advanced Study in Marine Biology,Faculty of Marine Sciences,Annumalai University Parangipettai - 60S 502.Tamil Nadu.India

出　　处：《Asian Pacific Journal of Tropical Medicine》2011年第9期722-726,共5页亚太热带医药杂志（英文版）

摘　　要：Objective:To explore the biomedical and pharmacological activity of Paracondactylis indicus (P.indicus).Paracondactylis sinensis(P.sinensis).Heteraclis magnified(H.magnified) and Stichadactyla haddoni(S.haddoni).Methods:The live sea anemones were kept inside the glass howl along with some amount of distilled water in an ice container for 15 min.During stress Condition,nemalocysts released from the tentacles were collected and centrifuged al 5 000 rpm for 15 min.The supernatant were collected ill separate cleaned beakers for lyophilisation.Results: The protein content of crude extracts was 15.2.28.7.18.2 and 35.4μg/mL.In hemolytic assay,the P.indicus was sensitive(16.842 HT/mg) on chicken blood but P.sinensis was less sensitive(1.114 HT/mg) on chicken and goal blood.Whereas H.magnified and S.haddoni showed hemolysis (0.879.0.903 HT/mg and 56.263.0.451 HT/mg) in chicken and goat blood.In antimicrobial assay, the methanol extract of P.indicus showed maximum inhibition zone of 9.7 mm against S.typhii and P.sinensis showed 9.8 mm against K.pneumonia in methanol and ethanol extracts.Whereas the H.magnified and S.haddoni showed maximum of 10 mm against S.typhii.K.pneumonia in methanol and ethanol extracts.Conclusions:The high toxic sea anemones may also contain some biologically active agents which has haemolytic,analgesic and anti-infilamatory activity.Objective:To explore the biomedical and pharmacological activity of Paracondactylis indicus (P.indicus).Paracondactylis sinensis(P.sinensis).Heteraclis magnified(H.magnified) and Stichadactyla haddoni(S.haddoni).Methods:The live sea anemones were kept inside the glass howl along with some amount of distilled water in an ice container for 15 min.During stress Condition,nemalocysts released from the tentacles were collected and centrifuged al 5 000 rpm for 15 min.The supernatant were collected ill separate cleaned beakers for lyophilisation.Results: The protein content of crude extracts was 15.2.28.7.18.2 and 35.4μg/mL.In hemolytic assay,the P.indicus was sensitive(16.842 HT/mg) on chicken blood but P.sinensis was less sensitive(1.114 HT/mg) on chicken and goal blood.Whereas H.magnified and S.haddoni showed hemolysis (0.879.0.903 HT/mg and 56.263.0.451 HT/mg) in chicken and goat blood.In antimicrobial assay, the methanol extract of P.indicus showed maximum inhibition zone of 9.7 mm against S.typhii and P.sinensis showed 9.8 mm against K.pneumonia in methanol and ethanol extracts.Whereas the H.magnified and S.haddoni showed maximum of 10 mm against S.typhii.K.pneumonia in methanol and ethanol extracts.Conclusions:The high toxic sea anemones may also contain some biologically active agents which has haemolytic,analgesic and anti-infilamatory activity.

关 键 词：NEMATOCYSTS Aqueous ANALGESIC activity HAEMOLYTIC and PHARMACOLOGICAL 

分 类 号：R285[医药卫生—中药学]