BACKGROUND Esophageal cancer constitutes one of the most aggressive malignant neoplasms associated with poor clinical outcomes.While surgical resection remains the cornerstone of curative intervention,optimization of ...
Supported by Beijing Medical Award Foundation of China,No.YXJL-2023-0638-0048.
BACKGROUND Hepatic artery infusion chemotherapy(HAIC)is a widely used local therapeutic approach for intermediate to advanced-stage hepatocellular carcinoma(HCC),exhibiting considerable efficacy.However,the prevalence...
funded by National Natural Science Foundation of China(No.12172092,82174488,and 82305416);Shanghai Key Laboratory of Acupuncture Mechanism and Acupoint Function(No.21DZ2271800);Shanghai Municipal Science and Technology Commission(No.23YF1418300);Scientific Research Project on Traditional Chinese Medicine of Shanghai Municipal Health Commission—Youth Guidance Category(No.2022QN018).
Objective The analgesic effect of acupuncture has been widely accepted.Nevertheless,the mechanism behind its analgesic effect remains elusive,thus impeding the progress of research geared toward enhancing the analgesi...
This work was financially supported by the National Natural Science Foundation of China(Nos.52161145410,52373126,and 52303173);Beijing University of Chemical Technology-China Japan Friendship Hospital Biomedical Translational Engineering Research Center Key Projects(No.XK2023-20);Grant from State Key Laboratory of Organic-Inorganic Composites(No.oic 202401005);the Fundamental Research funds for the Central Universities(No.ZY2453);the long-term subsidy mechanism from the Ministry of Finance and the Ministry of Education of PRC.
Pain management has become a prominent global health concern,affecting not only over the aspects of daily existence but also upon the holistic physical well-being.Conventional pain management methods have non-negligib...
Background:Pancreaticoduodenectomy(PD)is associated with severe postoperative pain.Optimized pain management can potentially elevate patients’postoperative quality of life.This study focused on comparing the analgesi...
The use of plants in traditional medicine is an alternative solution to address the adverse effects of conventional anti-inflammatories. This study evaluated the phytochemistry, anti-inflammatory, analgesic and toxici...
the National Natural Science Foundation of China(NSFC;grant no.21837003);the Joint Foundation of NSFC-Yunnan Province(grant no.U1502223);the Yunnan Revitalization Talent Support Program“Young Talent”Project,NSFC(grant no.81903521);the Natural Science Foundation of Yunnan Province,China(grant no.202001AT070067).
Phlegmine A(1),a novel type of Lycopodium alkaloid with a unique skeleton,was isolated from the rare and endangered herbal medicinal plant,Phlegmariurus phlegmaria.Spectroscopic methods and X-ray diffraction analysis ...
Objective:To assess the efficacy and safety of Sanjie Analgesic Capsule(SAC)in Chinese patients with endometriosis-associated pain.Methods:This was a multicenter,randomized,double-blind,placebo-controlled trial conduc...
Supported by Central Talent Training Project for the Reform and Development of Local Colleges and Universities(2020GSP16);Guidance Project of Key R&D Plan in Heilongjiang Province(GZ20220039).
Koumine is an indole alkaloid monomer extracted from the Chinese herb Gelsemium elegans,which has a variety of pharmacological effects.This paper provides a comprehensive summary of the pharmacological effects and mol...
Background: Elastomeric pumps (elastic balls into which analgesics or antibiotics can be inserted) push medicines through a catheter to a nerve or blood vessel. Since elastomeric pumps are small and need no power sour...