Antiarthritic effects of Ajuga bracteosa Wall ex Benth.in acute and chronic models of arthritis in albino rats  

作　　者：Gaurav Kaithwas Raju Gautam Sanjay M Jachak Arvind Saklani 

机构地区：[1]Department of Pharmaceutical Sciences,Assam University [2]Department of Natural Products,National Institute of Pharmaceutical Education and Research(NIPER) [3]Department of Natural Products,1-Nirlon Complex,Piramal Life Sciences

出　　处：《Asian Pacific Journal of Tropical Biomedicine》2012年第3期185-188,共4页亚太热带生物医学杂志（英文版）

基　　金：financially supported by National Institute ofPharmaceutical Education and Research

摘　　要：Objective:To evaluate the antiarthritic activity of Ajuga bracteosa using albino rats.Methods: The antiarthritic activity of 70%ethanolic extract of Ajuga bracteosa(EEAB) was evaluated against turpentine oil- and formaldehyde- induced acute non immunological and complete freund's adjuvant(CFA)-induced chronic immunological arthritis in albino rats.Results:EEAB showed a significant(P<0.05) and dose dependent inhibitory effect against acute and chronic models of arthritis.EEAB exhibited better antiarthritic activity than the standard aspirin.Conclusions: EEAB exhibits a significant and promising antiarthritic activity against acute and chronic arthritis and supports the traditional use of Ajuga bracteosa for rheumatism and other inflammatory diseases.Objective:To evaluate the antiarthritic activity of Ajuga bracteosa using albino rats.Methods: The antiarthritic activity of 70%ethanolic extract of Ajuga bracteosa(EEAB) was evaluated against turpentine oil- and formaldehyde- induced acute non immunological and complete freund's adjuvant(CFA)-induced chronic immunological arthritis in albino rats.Results:EEAB showed a significant(P<0.05) and dose dependent inhibitory effect against acute and chronic models of arthritis.EEAB exhibited better antiarthritic activity than the standard aspirin.Conclusions: EEAB exhibits a significant and promising antiarthritic activity against acute and chronic arthritis and supports the traditional use of Ajuga bracteosa for rheumatism and other inflammatory diseases.

关 键 词：Ajuga bracteosa ADJUVANT FORMALDEHYDE TURPENTINE CYCLOOXYGENASE 

分 类 号：R285.5[医药卫生—中药学]