Synthesis of silver nanoparticles using leaves of Catharanthus roseus Linn.G.Don and their antiplasmodial activities  

作　　者：Ponarulselvam S Panneerselvam C Murugan K Aarthi N Kalimuthu K Thangamani S 

机构地区：[1]Department of Zoology,School of Life Sciences,Bharathiar University [2]DRDO-BU Center for Life Sciences,Division of Entomology,Bharathiar University

出　　处：《Asian Pacific Journal of Tropical Biomedicine》2012年第7期574-580,共7页亚太热带生物医学杂志（英文版）

基　　金：supported by DRDO.Ministry of Defence,Goverment of India,New Delhi(Grant No.DLS/81/4822/LSRB-224/SHDD)

摘　　要：Objective:To develop a novel approach for the green synthesis of silver nanoparticles using aqueous leaves extracts of Catharanthus roseus(C.roseus) Linn.G.Don which has been proven aclive against malaria parasite Plasmodium falciparum(P.falciparum).Methods:Characterizations were determined by using ultraviolet-visible(UV-Vis) spectrophotometry,scanning electron microscopy(SEM).energy dispersive X-ray and X-ray diffraction.Results:SLM showed the formation of silver nanoparticles with an average size of 35-55 nm.X-ray diffraction analysts showed that the particles were crystalline in nature with face centred cubic structure of the hulk silver with the broad peaks at 32.4.46.4 and 28.0.Conclusions:It can be concluded that the leaves of C.roseus can he good source for synthesis of silver nanoparticle which shows aiitiplasmodial activity against P.falciparum.The important outcome of the study will he the development of value added products from medicinal plants C.roseus lor hionicdical and nanotechnology based industries.Objective:To develop a novel approach for the green synthesis of silver nanoparticles using aqueous leaves extracts of Catharanthus roseus(C.roseus) Linn.G.Don which has been proven aclive against malaria parasite Plasmodium falciparum(P.falciparum).Methods:Characterizations were determined by using ultraviolet-visible(UV-Vis) spectrophotometry,scanning electron microscopy(SEM).energy dispersive X-ray and X-ray diffraction.Results:SLM showed the formation of silver nanoparticles with an average size of 35-55 nm.X-ray diffraction analysts showed that the particles were crystalline in nature with face centred cubic structure of the hulk silver with the broad peaks at 32.4.46.4 and 28.0.Conclusions:It can be concluded that the leaves of C.roseus can he good source for synthesis of silver nanoparticle which shows aiitiplasmodial activity against P.falciparum.The important outcome of the study will he the development of value added products from medicinal plants C.roseus lor hionicdical and nanotechnology based industries.

关 键 词：Silver nanoparticles CATHARANTHUS roseus PLASMODIUM FALCIPARUM ANTIPLASMODIAL activity 

分 类 号：S853.7[农业科学—临床兽医学] TB383.1[农业科学—兽医学]