FALCIPARUM

作品数:89被引量:63H指数:4
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相关领域:医药卫生更多>>
相关作者:蒋琳郭敏刘晓雷清陈勇更多>>
相关机构:兰州生物制品研究所有限责任公司南通医学院中山医科大学南方医科大学更多>>
相关期刊:《Journal of Biomedical Science and Engineering》《World Journal of Clinical Infectious Diseases》《Open Journal of Epidemiology》《Science Bulletin》更多>>
相关基金:泰国研究基金World Health Organization国家自然科学基金国家重点基础研究发展计划更多>>
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Modeling and investigating malaria P.Falciparum and P.Vivax infections:Application to Djibouti data
《Infectious Disease Modelling》2024年第4期1095-1116,共22页Yahyeh Souleiman Liban Ismail Raluca Eftimie 
funded by CEALT(Centre d’Excellence Africain en Logistique et Transport)of the University of Djibouti;CEALT for their financial support;support from the MODCOV19 platform of the National Institute of Mathematical Sciences and their Interactions,(CNRS).
Malaria is an infectious and communicable disease,caused by one or more species of Plasmodium parasites.There are five species of parasites responsible for malaria in humans,of which two,Plasmodium Falciparum and Plas...
关键词:Falciparum and vivax models Reproduction number Stability analysis Sensitivity analysis FAST method LHS method Djibouti data 
Concurrent PIEZO1 activation and ATP2B4 blockade effectively reduce the risk of cerebral malaria and inhibit in vitro Plasmodium falciparum multiplication in red blood cells被引量:1
《Genes & Diseases》2023年第6期2210-2214,共5页Mathieu Adjemout Bruno Pouvelle Fatou Thiam Alassane Thiam Magali Torres Samia Nisar Babacar Mbengue Alioune Dieye Pascal Rihet Sandrine Marquet 
supported by the African Higher Education Centers of Excellence Project(CEA-SAMEF)at UCAD,the Pasteur Institute in Dakar,the Pasteur Institute in Paris,the French Embassy in Senegal,INSERM,and Aix-Marseille University.MA and SN were supported by a Ph.D.fellowship from the French Ministry of Research and the Higher Education Commission(HEC)in Pakistan,respectively;support from the French Government under the France 2030 Investment Plan,as part of the Initiative d'Excellence d'Aix-Marseille Université-A∗MIDEX-Institute MarMaRa(No.AMX-19-IET-007).
Malaria caused by the Plasmodium falciparum parasite is responsible for more than 240 million cases per year and killed 627,000 people in 2020,mostly African children.The malaria parasite is transmitted by mosquitos b...
关键词:MALARIA FALCIPARUM PLASMODIUM 
A heme-activatable probe and its application in the high-throughput screening of Plasmodium falciparum ring-stage inhibitors
《Signal Transduction and Targeted Therapy》2022年第6期1882-1884,共3页Sheng Liu Chunyan Wei Tian Liu Shuang-Gang Ma Chen Chen Hao Lin Lianhui Zhang Heng Wang Chong-Jing Zhang Shi-Shan Yu 
supported by the following funding:The Natural Science Foundation of China(No.21732008);CAMS Innovation Fund for Medical Sciences(CIFMS)(2016-I2M-3-010,2017-I2M-4-005,2016-I2M-1-019).
Dear Editor,The resistance of Plasmodium falciparum to artemisinin derivatives(ARTs)in Asian,African and South American countries is a pressing global concern.Heme is an important biomarker of malaria parasites and is...
关键词:FALCIPARUM HEME PLASMODIUM 
Investigation of Plasmodium falciparum Resistance Biomarkers among Primary School Children in Western Kenya
《American Journal of Molecular Biology》2022年第2期43-53,共11页Otilmoi Poul Stephen Tonny Teya Nyandwaro Robinson Mugasiali Irekwa Rebecca Wanjiku Waihenya Matthew Mutinda Munyao Peter Kipkemboi Rotich Caroline Wangui Njoroge Anne Wanjiru Mwangi Joanne Jepkemei Yego Nicole Sian Tanchu Dawala Koromtili Oumar Grace Ngendo Kanyita Primrose Muthoni Ndungu Samson Muuo Nzou 
Background: A marked decrease in malaria-related deaths worldwide has been attributed to the administration of effective antimalarials against Plasmodium falciparum. However, the continuous spread of P. falciparum res...
关键词:P. falciparum CHLOROQUINE Drug Resistance MALARIA P. falciparum Chloroquine Resistance Transporter Gene MUTATIONS 
Investigation of the effect of malaria and home-based oral chloroquine treatment on biochemical indices of P.falciparum malaria infection in children under 5 years in jos metropolis
《Infectious Diseases Research》2022年第1期29-33,共5页Olomu Segun Afolabi Samuel Yusufu Gazuwa Garba Ibrahim Hassan Okolo Selina Nnuaku 
Background:In Nigeria,malaria is a leading cause of hospital admission and death.The country accounts for highest malaria cases and deaths globally.About 25% of all malaria cases and deaths in the world occurs in Nige...
关键词:CHLOROQUINE P.falciparum CHILDREN MALARIA pathogenesis 
Azacarbazole n-3 and n-6 polyunsaturated fatty acids ethyl esters nanoemulsion with enhanced efficacy against Plasmodium falciparum被引量:2
《Bioactive Materials》2021年第4期1163-1174,共12页Anna Jaromin Silvia Parapini Nicoletta Basilico Magdalena Zaremba-Czogalla Agnieszka Lewi´nska Agnieszka Zag´orska Maria Walczak Bozena Tyliszczak Aleksandra Grzeszczak MarcinŁukaszewicz Łukasz Kaczmarek Jerzy Gubernator 
the statutory activity of subsidy from the Polish Ministry of Science and Higher Education for the Faculty of Biotechnology and Faculty of Chemistry of the University of Wroclaw and by Ministero dell’Istruzione,dell’Universit`a e della Ricerca[PRIN 2015.4JRJPP_004].Publication costs were supported by Wroclaw Center of Biotechnology program“The Leading National Research Center(KNOW)for years 2014-2018”.
Alternative therapies are necessary for the treatment of malaria due to emerging drug resistance.However,many promising antimalarial compounds have poor water solubility and suffer from the lack of suitable delivery s...
关键词:Azacarbazoles Flax oil n-3 and n-6 polyunsaturated fatty acids ethyl ESTERS NANOEMULSION P.falciparum MALARIA 
Evaluation of antiplasmodial properties in 15 selected traditional medicinal plants from India
《Journal of Integrative Medicine》2020年第1期80-85,共6页Yogesh Subhash Biradar Swathi Bodupally Harish Padh 
the Indian Council of Medical Research,New Delhi,India for financial support.
Objective:The objective of this study was to evaluate the in vitro antiplasmodial properties against malaria parasite in 15 plants mentioned in Indian traditional medicine texts.Methods:In vitro antiplasmodial activit...
关键词:Medicinal plants PLASMODIUM FALCIPARUM Schizont maturation INHIBITION ASSAY LACTATE dehydrogenase INHIBITION ASSAY Cytotoxicity 
DNA Gene Expression to Study Immunologic Mechanisms for the Long-Term Cure of Malaria in Babies and Children in South-Western Nigeria
《Advances in Biological Chemistry》2019年第2期68-87,共20页Jerry T. Thornthwaite Akanni E. Olufemi Ayankunle A. Ademola O. A. T. Alli 
Malaria infection has been a very serious public health problem in Nigeria and most parts of Africa. Development of antimalarial treatments capable of providing a permanent cure for malaria has been a herculean task f...
关键词:TriantimalTM NutraNanoSpheresTM IMMUNITY qPCR Gene Expression PLASMODIUM FALCIPARUM 
Novel dual inhibitors against FP-2 and PfDHFR as potential antimalarial agents: Design, synthesis and biological evaluation
《Chinese Chemical Letters》2019年第1期250-254,共5页Wenhua Chen Xue Yao Zhenghui Huang Fei Mao Longfei Guan Yun Tang Hualiang Jiang Jian Li Jin Huang Lubin Jiang Jin Zhu 
Financial support for this research provided by the National Natural Science Foundation of China (Nos. 21372001 and 21672064);the "Shu Guang" Project supported by the Shanghai Municipal Education Commission and Shanghai Education Development Foundation (No. 14SG28)
Resistance to malaria parasites has quickly developed to almost all used antimalarial drugs. Cysteine protease falcipain-2(FP-2) and Plasmodium falciparum dihydrofolate reductase(PfDHFR) have crucial roles, which are ...
关键词:ANTIMALARIAL DRUG PLASMODIUM FALCIPARUM FP-2 PfDHFR Dual INHIBITOR 
Effect of Primaquine on Gametocyte Carriage in the Case-Management of Uncomplicated Falciparum Malaria with Acts: Nigerian Perspective
《Advances in Infectious Diseases》2018年第2期39-53,共15页A. B. Tsuung S. L. Pitmang F. L. Dassak 
Background: Drugs that kill or inhibit sexual stages of Plasmodium such as Primaqiune (PQ) could potentially amplify or synergize the impact of first line antimalarials by blocking transmission to mosquitoes. This stu...
关键词:Malaria Artemisinin-Based Combination Therapy Plasmodium FALCIPARUM PRIMAQUINE GAMETOCYTES Dihydroartemisinin-Piperaquine 
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