云南高校图书馆联盟文献共享服务平台- HEME

HEME: 作品数：133被引量：309H指数：9; 导出分析报告; 相关领域：医药卫生生物学更多>>; 相关作者：王志强王韵华吴厚铭肖爽黄仲贤更多>>; 相关机构：昆明医科大学中国科学院南华大学华中科技大学更多>>; 相关期刊：更多>>; 相关基金：国家自然科学基金国家重点基础研究发展计划河北省自然科学基金上海市教育委员会重点学科基金更多>>

溶血性输血反应中heme对小鼠肝细胞的直接损伤分析: 《中文科技期刊数据库(全文版)医药卫生》2025年第3期217-222,共6页胡秀珍; 以溶血性输血反应中的肝细胞为对象,分析heme直接损伤肝细胞的效应。本研究通过注射人源血浆建立急性溶血性输血反应小鼠模型;静脉注射溶血性输血反应产物heme建立小鼠肝损伤模型;体外heme处理小鼠原代肝细胞建立细胞损伤模型;用生化检...; 关键词：溶血性输血反应 HEME 肝细胞

Complexation of CcmB with CcmACD safeguards heme translocation for cytochrome c maturation: 《mLife》2025年第1期29-44,共16页Yuanyou Xu Wei Wang Qianrou Zhang Sirui Han Jiahao Wang Shihua Wu Haichun Gao; supported by the National Natural Science Foundation of China(31930003 and 41976087);the National Key R&D Program of China(2018YFA0901300).; Cytochrome c maturation(CCM),a posttranslational modification involving covalent attachment of heme to polypeptides(apocyt c),is essential for the activity and cellular function of cytochromes c.Here,we identify and s...; 关键词：CcmABCD cytochrome c cytochrome c biosynthesis HEME heme translocation

Catalytic performances of engineered and artificial heme peroxygenases: 《Chinese Journal of Catalysis》2025年第2期35-51,共17页Yiping Jiang Zaw Ko Latt Zhiqi Cong; 科技部国家重点研发计划(2023YFA0915500);国家自然科学基金(32371311,32471325,22207112);泰山学者项目;中国科学院国际人才计划(2019PB0167);中国科学院青岛生物能源与过程研究所自主部署项目(S202302).; Heme peroxygenases exhibit remarkable catalytic versatility in facilitating a wide array of oxidative reactions under mild conditions,eliminating the need for coenzymes and intricate electron transport systems.This un...; 关键词：Peroxygenases Hydrogen peroxide Cytochrome P450 peroxygenases Unspecific peroxygenases Protein engineering

A herbal pair of Scutellaria barbata D.Don and Scleromitrion diffusum(Willd.)R.J.Wang induced ferroptosis in ovarian cancer A2780 cells via inducing heme catabolism and ferritinophagy: 《Journal of Integrative Medicine》2024年第6期665-682,共18页Zhen Wang Min Liu Guang-xing Li Liu Zhang Kai-yue Ding Si-qi Li Bing-qing Gao Peng Chen Hyok-Chol Choe Lun-yue Xia Yu-tong Yang Yi Liu Xue Sui Jun-nan Ma Lin Zhang; supported by the National Natural Science Foundation of China(No.81873195);the Applied Basic Research Program of Liaoning Province(No.2023JH2/101300103);the Liaoning Revitalization Talents Program(No.XLYC1907113);the Dalian Medical University Foundation for Teaching Reform Project of Undergraduate Innovative Talents Training(No.111807010303)。; Objective:Despite the combination of Scutellaria barbata D.Don and Scleromitrion diffusum(Willd.)R.J.Wang(SB-SD)being a recognized Chinese medicinal herbal pair that is commonly used in the treatment of ovarian cancer...; 关键词：Scutellaria barbata D.Don Scleromitrion diffusum(Willd.)R.J.Wang Ovarian cancer Transcriptomic Proteomic Ferroptosis Heme catabolism Ferritinophagy

Performance evaluation of the effect of humic acid on Anammox granular sludge:Apparent morphology,nitrogen removal and microbial community被引量：1: 《Journal of Environmental Sciences》2024年第10期148-158,共11页Wenhui Huang Peiling Xu Xiang Li Yong Huang Hao Sun Wei Li Mao Zhang Miao Shi Yan Yuan; This work was supported by the Natural Science Foundation of China(No.51938010);the Jiangsu Collaborative Innovation Center of Technology and Material of Water Treatment(No.XTCXSZ2022-1).; Humic acid(HA)is a typical refractory organicmatter,so it is of great significance to investigate its effect on the performance of Anammox granular sludge.When the dosage ofHA≤50 mg/L,HA promotes the total nitrogen r...; 关键词：ANAMMOX Landfill leachate Humic acid HEME Microbial community Enzyme activity

Innate immune sensing of danger signals: novel mechanism of heme complex-mediated lytic cell death: 《Signal Transduction and Targeted Therapy》2024年第10期4175-4177,共3页Chintan Chhatbar Michael Schulz Roman Sankowski; We acknowledge support by the Open Access Publication Fund of the University of Freiburg enabled and organized by Projekt DEAL;R.S.is supported by the IMMediate Advanced Clinician Scientist-Program,Department of Medicine II,Medical Center,University of Freiburg and Faculty of Medicine,University of Freiburg,funded by the Bundesministerium für Bildung und Forschung(Federal Ministry of Education and Research),01EO2103;Furthermore,R.S.is supported by the Fritz Thyssen Foundation.M.S.is supported by the German Research Foundation(DFG,SCHU3696/2-1).Open Access funding enabled and organized by Projekt DEAL.; In their recent publication in Cell,Sundaram,and colleagues identified a novel role for NOD-like receptor(NLR)family CARD domain containing 5(NLRC5)in heme-mediated cell death and inflammation.1 This process is initia...; 关键词：DEATH HEME NLR

Heme homeostasis and its regulation by hemoproteins in bacteria: 《mLife》2024年第3期327-342,共16页Yingxi Li Sirui Han Haichun Gao; This work was supported by the National NaturalScience Foundation of China(Nos.31930003 and 41976087)。; Heme is an important cofactor and a regulatory molecule involved in various physiological processes in virtually all living cellular organisms,and it can also serve as the primary iron source for many bacteria,particu...; 关键词：HEME heme acquisition and utilization heme export heme homeostasis HEMOPROTEIN

N-methylation of histidine to tune tautomeric preferences in histidine-heme coordination and enzyme-mimetic catalysis: 《Smart Molecules》2024年第3期139-145,共7页Ruikai Du Yunbo Lv Haifeng Wu Baoli Zhang Yuanxi Liu Shichao Xu Shan Li Zhen-Gang Wang; supported by the National Natural Science Foundation of China(No.52173194);Beijing Natural Science Foundation(No.2232017);Fundamental Research Funds for the Central Universities(No.buctrc201902).; Enzymes with active sites involving histidine selectively utilize either theδ-orε-nitrogen atom(N_(δ)or N_(ε))of the histidine imidazole for catalysis.However,evaluating the impact of N_(δ)and N_(ε)is difficult,...; 关键词：heme-dependent enzyme HISTIDINE self-assembly tautomeric preference

Pathological significance of heme oxygenase-1 as a potential tumor promoter in heme-induced colorectal carcinogenesis: 《Cancer Pathogenesis and Therapy》2024年第2期65-73,共9页Rachitha Singhabahu Sujani M Vinod Gopalan; The significance of the heme-metabolizing enzyme heme oxygenase-1(HMOx1)in the pathogenesis of colorectal cancer(CRC)has not been fully explored.HMOx1 cytoprotection is imperative to limit oxidative stress.However,its...; 关键词：HEME CARCINOGENESIS Colorectal cancer HMOX1 PROMOTER

Multi-modular metabolic engineering of heme synthesis in Corynebacterium glutamicum: 《Synthetic and Systems Biotechnology》2024年第2期285-293,共9页Qiuyu Yang Xi Sun Hong Wang Tao Chen Zhiwen Wang; This work was financially supported by the National Key Research and Development Program of China,China(2021YFC2100700);the National Natural Science Foundation of China,China(NSFC-22278312).; Heme,an iron-containing porphyrin derivative,holds great promise in fields like medicine,food production and chemicals.Here,we developed an engineered Corynebacterium glutamicum strain for efficient heme production by...; 关键词：Corynebacterium glutamicum HEME Biosynthetic pathways Metabolic engineering

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