ANTIPLASMODIAL

作品数：35被引量：40H指数：3
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In silico antiplasmodial effects of phytocompounds derived from Andrographis paniculata on validated drug targets of different stages of Plasmodium falciparum
《Infectious Diseases Research》2024年第2期1-11,共11页Funmilayo I.D.Afolayan Sayo Ebenezer Oladokun 
Background:Andrographis paniculata has been widely reported as an herbal plant for malaria treatment.The increasing rate of resistance to recommended antimalarial drugs has justified the need for a continuous search f...
关键词：Plasmodium falciparum drug targets Andrographis paniculata molecular docking molecular dynamics 
Antiplasmodial mechanism of Lawsonia inermis: An in silico based investigation被引量：1
《Infectious Diseases Research》2024年第1期8-26,共19页Ridwan Abiodun Salaam Funmilayo I.D.Afolayan 
Background:Lawsonia inermis has been widely reported to be used as an herbal treatment for Malaria.However,despite several experimental studies about its antimalarial activities,the approach through which the herbal p...
关键词：Lawsonia inermis computational studies plasmodium falciparum network pharmacology molecular dynamic 
A narrative review on inhibitory effects of edible mushrooms against malaria and tuberculosis-the world’s deadliest diseases
《Food Science and Human Wellness》2023年第4期942-958,共17页Ashaimaa Y.Moussa Baojun Xu 
supported by two grants(UIC202007 and UIC202107)from BNU-HKBU United International College.
The isolated secondary metabolites from 39 edible mushrooms are reported,among which 107 compounds were active,61 demonstrated antitubercular activities with IC_(50) range of 0.2-50μg/mL and 46 manifested antimalaria...
关键词：ANTITUBERCULOSIS ANTIPLASMODIAL MACROFUNGI MUSHROOMS Structure activity relationship 
Evaluation of Antiplasmodial Effect of Methanol Leaf Extract and Fractions of Eucalyptus camadulensis (Denhn) in Albino Wistar Mice
《American Journal of Plant Sciences》2023年第6期662-676,共15页Amarachi Akachukwu Moses Ikegbunam Emmanuel Enyi Theresa Osarunwese Ifeyinwa Onochie-Igbinedion Harrison Abone Dorothy Ezeagwuna Joy Nnanna Chibueze Ihekwereme Chukwuemeka Nworu 
Nigeria is one of the malaria-endemic countries, where the treatment of malaria has relied heavily on natural and traditional medicines. This study was designed to investigate and ascertain the preference of Eucalyptu...
关键词：Eucalyptus camadulensis ANTIPLASMODIAL 
LC-MS Phytochemical Profiles of Phenolic Compounds and Antimicrobial, Antioxidant, and Antiplasmodial Activities of Ethanol Extracts of Pycnostachys erici-rosenii R.E.Fr and Leucas martinicensis (Jack.) R.Br (Lamiaceae)
《Advances in Biological Chemistry》2023年第6期209-227,共19页Uwikunda Serondo Héritier Nizigiyimana Libérata Pius Tshimankinda Mpiana Nyamangyoku Ishibwela Obedi Ngezahayo Jérémie Dan Cristian Vodnar Daniela Hanganu Ioana Matei Sanda Andrei 
This study has been conducted to analyze the chemical composition and antimicrobial, antioxidant and antiplasmodial properties of ethanol extracts of Pycnostachys erici-rosenii R.E.Fr and Leucas martinicensis (Jack.) ...
关键词：Pycnostachys erici-rosenii Leucas martinicensis Phytochemical Profile Antimicrobial Activity Antioxidant Activity Antiplasmodial Activity 
Prioritised identification of structural classes of natural products from higher plants in the expedition of antimalarial drug discovery
《Natural Products and Bioprospecting》2023年第1期348-367,共20页Phanankosi Moyo Luke Invernizzi Sephora M.Mianda Wiehan Rudolph Andrew W.Andayi Mingxun Wang Neil R.Crouch Vinesh J.Maharaj 
The emergence and spread of drug-recalcitrant Plasmodium falciparum parasites threaten to reverse the gains made in the fight against malaria.Urgent measures need to be taken to curb this impending challenge.The highe...
关键词：Natural products Compound classes PHYTOCHEMICALS Plasmodium falciparum Antiplasmodial drug resistance MALARIA Drug development 
Leveraging off higher plant phylogenetic insights for antiplasmodial drug discovery
《Natural Products and Bioprospecting》2023年第1期382-399,共18页Phanankosi Moyo Luke Invernizzi Sephora M.Mianda Wiehan Rudolph Warren A.Andayi Mingxun Wang Neil R.Crouch Vinesh J.Maharaj 
The antimalarial drug-resistance conundrum which threatens to reverse the great strides taken to curb the malaria scourge warrants an urgent need to find novel chemical scaffolds to serve as templates for the developm...
关键词：Natural products Plants PHYLOGENETICS MALARIA DRUG-RESISTANCE ‘Hot’plants 
Structure modification,antialgal,antiplasmodial,and toxic evaluations of a series of new marine-derived 14-membered resorcylic acid lactone derivatives被引量：4
《Marine Life Science & Technology》2022年第1期88-97,共10页Wei-Feng Xu Na-Na Wu Yan-Wei Wu Yue-Xuan Qi Mei-Yan Wei Laura M.Pineda Michelle G.Ng Carmenza Spadafora Ji-Yong Zheng Ling Lu Chang-Yun Wang Yu-Cheng Gu Chang-Lun Shao 
supported by the Program of National Natural Science Foundation of China(Nos.U1706210,41776141,42006092,41322037 and 41830535);the Fundamental Research Funds for the Central Universities(No.201841004);the Marine S&T Fund of Shandong Province for Pilot National Laboratory for Marine Science and Technology(Qingdao)(No.2018SDKJ0403-2);the Research Fund of State Key Laboratory for Marine Corrosion and Protection of Luoyang Ship Material Research Institute(LSMRI)[No.KF190402],and the Taishan Scholars Program,China(No.tsqn20161010);funded by a SENACYT grant(FID17-095)and partially by the National System of Investigators(SNI)of Panama.
Marine natural products play critical roles in the chemical defense of many marine organisms and are essential,reputable sources of successful drug leads.Sixty-seven 14-membered resorcylic acid lactone derivatives 3–...
关键词：Marine natural product 14-Membered resorcylic acid lactone Zeaenol SEMISYNTHESIS Antialgal activity Antiplasmodial activity 
Antioxidant and Antiplasmodial Activities of Extracts from <i>Gardenia erubescens</i>Stapf et Hutch. and <i>Fadogia agrestis</i>Schweinf. ex Hiern. (Rubiaceae)被引量：1
《Open Journal of Applied Sciences》2020年第11期675-687,共13页Mariama Kaba Combasséré-Chérif Hadidjatou Belem Benjamin Koama Assetou Sawadogo Sandrine Nadège Da Windmi Kagambéga Anne-Flora Drabo Roland Nâg-Tiéro Meda George Anicet Ouédraogo 
Two medicinal plants, Gardenia erubescens and
《International Journal of Organic Chemistry》2020年第1期1-16,共16页Angelbert F. Awantu Yannick Stephane F. Fongang Godfred A. Ayimele Edouard A. Nantia Patrick V. T. Fokou Fabrice F. Boyom Celine K. Ngwang Bruno N. Lenta Silvère A. Ngouela 
Two novel Schiff bases, 3-[1-(2-(phthalazin-1-yl)hydrazono)ethyl)-1,3-oxa- zinane (PHEO) and 2-[(2-(phthalazin-1-yl)hydrazono)methyl]phenol (PHMP), derived from hydralazine hydrochloride, an effective drug against hyp...
关键词：HYDRALAZINE HYDROCHLORIDE SCHIFF Bases ANTIMICROBIAL ANTI-OXIDANT Anti-Plasmodial Activities 
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