HYDRALAZINE

作品数:15被引量:19H指数:3
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相关领域:医药卫生更多>>
相关作者:赵军赵国海张义胜夏亚斌李云庆更多>>
相关机构:皖南医学院弋矶山医院淮海工学院第四军医大学更多>>
相关期刊:《American Journal of Analytical Chemistry》《Frontiers of Medicine》《Open Journal of Physical Chemistry》《Neural Regeneration Research》更多>>
相关基金:安徽省高校省级自然科学研究项目更多>>
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Method Verification and Validation of Hydralazine Hydrochloride: Spectrophotometric Analysis in Pure and Pharmaceutical Formulations
《American Journal of Analytical Chemistry》2024年第7期219-228,共10页Laila Abdullah Alshatti 
The new method proposed is based on the formation of hydralazine-Bromophenol blue ion pair simply and without further extraction or heating. The ion pair was prepared in the presence of pH 3 citrate buffer forming a y...
关键词:SPECTROPHOTOMETRY Validation Hydralazine Hydrochloride International Conference on Harmonization Q2 (R1) 
Utilization of hydralazine as a reactive matrix for enhanced detection and on-MALDI-target derivatization of saccharides
《Chinese Chemical Letters》2024年第5期386-391,共6页Dan Ouyang Huan Huang Yanting He Jiajing Chen Jiali Lin Zhuling Chen Zongwei Cai Zian Lin 
supported by a grant from the National Natural Science Foundation of China(Nos.22274021,21974021 and 22036001);the Natural Science Foundation of Fujian Province(No.2022J01535);the Major Project of Science and Technology of Fujian Province(No.2020HZ06006)。
Saccharides are a sort of ubiquitous and vital molecules within the whole life.However,the application of saccharides analysis with matrix-assisted laser desorption/ionization mass spectrometry(MALDI-MS)is restricted ...
关键词:HYDRALAZINE Reactive matrix On-MALDI-target derivatization Saccharides 
Retraction Note:Hydralazine Promotes Central Nervous System Recovery after Spinal Cord Injury by Suppressing Oxidative Stress and Inflammation through Macrophage Regulation
《Current Medical Science》2024年第2期462-462,共1页Xin QUAN Teng MA Kai GUO Huan WANG Cai-yong YU Chu-chu QI Bao-qiang SONG 
The Editor-in-Chief has retracted this article on the corresponding authors'request.The corresponding authors on behalf of all the authors stated that the data presented in this article does not belong to the named au...
关键词:behalf stated China. 
Hydralazine represses Fpn ubiquitination to rescue injured neurons via competitive binding to UBA52被引量:1
《Journal of Pharmaceutical Analysis》2024年第1期86-99,共14页Shengyou Li Xue Gao Yi Zheng Yujie Yang Jianbo Gao Dan Geng Lingli Guo Teng Ma Yiming Hao Bin Wei Liangliang Huang Yitao Wei Bing Xia Zhuojing Luo Jinghui Huang 
supported by grants from the National Natural Science Foundation of China(Grant Nos.:82122043,81972052,81902213,82201537,and 81730065);the China Postdoctoral Science Foundation(Grant Nos.:2021M693946 and 2019M653967).
A major impedance to neuronal regeneration after peripheral nerve injury (PNI) is the activation of various programmed cell death mechanisms in the dorsal root ganglion. Ferroptosis is a form of programmed cell death ...
关键词:Ferroptosis UBA52 FERROPORTIN UBIQUITINATION HYDRALAZINE Peripheral nerve injury 
Hydralazine Promotes Central Nervous System Recovery after Spinal Cord Injury by Suppressing Oxidative Stress and Inflammation through Macrophage Regulation被引量:1
《Current Medical Science》2023年第4期749-758,共10页Xin QUAN Teng MA Kai GUO Huan WANG Cai-yong YU Chu-chu QI Bao-qiang SONG 
supported by the National Natural Science Foundation of China Young Scientists Fund(No.81801216,No.81802143,No.81901966);the China Postdoctoral Foundation(No.2018M633748).
Objective:This study aims to investigate the effects of hydralazine on inflammation induced by spinal cord injury(SCI)in the central nervous system(CNS)and its mechanism in promoting the structural and functional reco...
关键词:spinal cord injury proinflammation oxidative stress MACROPHAGE acrolein scavenger 
Labetalol versus Hydralazine in the Management of Severe Pre-Eclampsia at Tertiary Hospitals in a Low-Resource Setting: A Randomised Controlled Trial
《Open Journal of Obstetrics and Gynecology》2023年第6期1058-1067,共10页Uzoma Otutoaja Adeyemo Olabisi Timothy Emmanuel Olumide Adewara Olufunmilayo Victoria Adebara Augustine Adebayo Adeniyi Babatunde Sunday Awoyinka Raymond Akujuobi Okere Idowu Oluseyi Adebara Adewumi Bakare Mojisola Olumide Ayankunle 
Objective: Intravenous labetalol and hydralazine are both considered first-line medications for the management of acute-onset, severe hypertension in pregnant and postpartum women. The study compared the efficacy and ...
关键词:Blood Pressure HYDRALAZINE LABETALOL Low-Resource Setting Severe Pre-Eclampsia Side Effects 
Synthesis, Molecular Structure, Anti-Plasmodial, Antimicrobial and Anti-Oxidant Screening of (E)-1-(Phthalazin-1-yl)-1-[(Pyridin-2-yl)Ethylidene]Hydralazine and 1-[2-(1-(pyridine-3- yl)ethylidene)hydrazinyl]phthalazine被引量:1
《International Journal of Organic Chemistry》2021年第3期91-105,共15页Angelbert F. Awantu Godfred A. Ayimele Jean Jules K. Bankeu Edouard A. Nantia Patrick V. T. Fokou Fabrice F. Boyom Emmanuel N. Nfor Bruno N. Lenta Silvère A. Ngouela 
Two new hydralazine hydrochloride-derived Schiff bases: (E)-1-(Phthalazin-
关键词:Schiff Base Hydralazine Hydrochloride Anti-Plasmodial Activity Antimicrobial Activity Anti-Oxidant Activity 
Novel Hydralazine Schiff Base Derivatives and Their Antimicrobial, Antioxidant and Antiplasmodial Properties
《International Journal of Organic Chemistry》2020年第1期1-16,共16页Angelbert F. Awantu Yannick Stephane F. Fongang Godfred A. Ayimele Edouard A. Nantia Patrick V. T. Fokou Fabrice F. Boyom Celine K. Ngwang Bruno N. Lenta Silvère A. Ngouela 
Two novel Schiff bases, 3-[1-(2-(phthalazin-1-yl)hydrazono)ethyl)-1,3-oxa- zinane (PHEO) and 2-[(2-(phthalazin-1-yl)hydrazono)methyl]phenol (PHMP), derived from hydralazine hydrochloride, an effective drug against hyp...
关键词:HYDRALAZINE HYDROCHLORIDE SCHIFF Bases ANTIMICROBIAL ANTI-OXIDANT Anti-Plasmodial Activities 
基于共振光散射光谱法测定药品中盐酸肼屈嗪含量被引量:3
《光散射学报》2019年第1期54-59,共6页牟城健 王振 许钟元 李银华 马卫兴 李树安 
为了研究药品中盐酸肼屈嗪含量检测的新方法,本文采用共振光散射光谱法以Clark-Lubs缓冲液为介质分析盐酸肼屈嗪与十二烷基苯磺酸钠反应的光散射强度参数关系。研究发现:在pH 1.4的Clark-Lubs缓冲介质中适量盐酸肼屈嗪与十二烷基苯磺酸...
关键词:HYDRALAZINE HYDROCHLORIDE SODIUM dodecyl BENZENE SULFONATE Resonance light scattering spectroscopy 
Corrosion Inhibitory Studies of Novel Schiff Bases Derived from Hydralazine Hydrochloride on Mild Steel in Acidic Media
《Open Journal of Physical Chemistry》2018年第1期15-32,共18页Romanus N. Njong Bridget N. Ndosiri Emmanuel N. Nfor Offiong E. Offiong 
The inhibition performance of 1-hydralazinophthalazine (HPZ) (1), and synthesized1-(2-[(5-methylfuran-2-yl)methylene)] hydrazono) phthalazine (MFHPZ) (2), 1-(phthalazin-1(2H)-one) [(pyridin-2-yl) ethylidene] hydrazone...
关键词:MILD Steel HYDRALAZINE HYDROCHLORIDE WEIGHT Loss Corrosion INHIBITION 
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