A case report of herpetic and candidal esophagitis in an immunocompetent adult  

作　　者：Vishwanath Sathyanarayanan Abdul Razak M Mukhyprana Prabhu Kavitha Saravu Ganesh Pai C Anuradha K Rao 

机构地区：[1]Department of Internal Medicine,Kasturba Medical College,Manipal,Manipal University [2]Department of Gastroenterology and Hepatology,Kasturba Medical College,Manipal,Manipal University [3]Department of Pathology,Kasturba Medical College,Manipal,Manipal University,Karnataka,India

出　　处：《Asian Pacific Journal of Tropical Biomedicine》2011年第3期251-252,共2页亚太热带生物医学杂志（英文版）

摘　　要：Reports of combined candidal and herpetic esophagitis in immunocompetent states are rare and sporadic.A 44-year-old previously healthy lady presented with a one week history of progressive dysphagia,odynophagia and fever.Esophagogastroduodenoscopy(EGD) showed extensive desquamation of the entire esophagus except for distal 4 cm.Histopathological examination revealed ulcerated and inflamed squamous epithelium with the margin of ulcer showing a few overhanging squamous cells with dense eosinophilic cytoplasm,multinucleated and faceted nuclei with glassy chromatin,and an occasional Cowdry type A intranuclear inclusion bodies.Few candidal spores were seen in the underlying stroma.Intravenous acyclovir,fluconazole and pantoprazole were initiated.Oral analgesics were given for pain relief.She was treated for a total of 14 days.She showed significant improvement and was tolerating oral intake after discharge.The patient was asymptomatic with no evidence of recurrence at a 2-month follow-up.Reports of combined candidal and herpetic esophagitis in immunocompetent states are rare and sporadic.A 44-year-old previously healthy lady presented with a one week history of progressive dysphagia,odynophagia and fever.Esophagogastroduodenoscopy(EGD) showed extensive desquamation of the entire esophagus except for distal 4 cm.Histopathological examination revealed ulcerated and inflamed squamous epithelium with the margin of ulcer showing a few overhanging squamous cells with dense eosinophilic cytoplasm,multinucleated and faceted nuclei with glassy chromatin,and an occasional Cowdry type A intranuclear inclusion bodies.Few candidal spores were seen in the underlying stroma.Intravenous acyclovir,fluconazole and pantoprazole were initiated.Oral analgesics were given for pain relief.She was treated for a total of 14 days.She showed significant improvement and was tolerating oral intake after discharge.The patient was asymptomatic with no evidence of recurrence at a 2-month follow-up.

关 键 词：HERPES SIMPLEX CANDIDA ESOPHAGITIS IMMUNOCOMPETENT 

分 类 号：R571[医药卫生—消化系统]