A facile synthesis of goodyeroside A from (S)-malic acid  

作　　者：Feng Zhang  Jun Wei  DaLi Yin  HaiHong Huang YanHong Zhang 

机构地区：[1] Institute of Materia Medica, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, 100050, China [2] National Engineering Research Center for the Development of New Drugs, Beijing, 102600, China

出　　处：《Science China Chemistry》2009年第12期2176-2179,共4页中国科学（化学英文版）

摘　　要：Goodyeroside A 1,a natural product with hepatoprotective activity,was efficiently synthesized in a total yield of 47% in five steps starting from (S)-malic acid. The spectral data of the target compound 1 is identical with those of the natural product.Goodyeroside A 1, a natural product with hepatoprotective activity, was efficiently synthesized in a total yield of 47% in five steps starting from (S)-malic acid. The spectral data of the target compound 1 is identical with those of the natural product.

关 键 词：goodyeroside A ESTERIFICATION protecting GROUP GLYCOSIDE LACTONIZATION 

分 类 号：O621.25[理学—有机化学]