GENETIC POLYMORPHISM OF STR LOCI IN CHINESE DRUNGS  

作　　者：赖江华 郑海波 朱波峰 李生斌 

出　　处：《Journal of Pharmaceutical Analysis》2002年第1期30-32,共3页药物分析学报（英文版）

基　　金：ThesubjectwassupportedbyNationalNatureScienceFoundationofChina (No .39970 40 1)

摘　　要：Objective To study the STR polymorphism in Chinese Drungs. Methods The genetic distributions of 15 STR loci and Amelogenin locus were generated through coamplification, genescan and genotype from 65 Drungs. Results There were 144 STR and 2 Amelogenin alleles in Drung nationality, with their frequencies ranging from 0.0077 to 0.7846, H 0.3723～0.8639, DP 0.5567～0.9548, EPP 0.2738～0.8358, and PIC 0.3461～0.8456, the accumulative DP 0.99999998 and EPP 0.99999894. Conclusion The study founded a basis for the genetic structure of Chinese ethnic groups,which is useful for the application to anthropology and forensic science.Objective To study the STR polymorphism in Chinese Drungs. Methods The genetic distributions of 15 STR loci and Amelogenin locus were generated through coamplification, genescan and genotype from 65 Drungs. Results There were 144 STR and 2 Amelogenin alleles in Drung nationality, with their frequencies ranging from 0.0077 to 0.7846, H 0.3723～0.8639, DP 0.5567～0.9548, EPP 0.2738～0.8358, and PIC 0.3461～0.8456, the accumulative DP 0.99999998 and EPP 0.99999894. Conclusion The study founded a basis for the genetic structure of Chinese ethnic groups,which is useful for the application to anthropology and forensic science.

关 键 词：Drung nationality STR polymorphism coamplification GENESCAN 

分 类 号：R394[医药卫生—医学遗传学]