云南高校图书馆联盟文献共享服务平台- GENESCAN

GENESCAN: 作品数：11被引量：55H指数：4; 导出分析报告; 相关领域：医药卫生更多>>; 相关作者：李扬秋汪明春杜欣张林廖继东更多>>; 相关机构：暨南大学广东省人民医院四川大学北京协和医院更多>>; 相关期刊：《Journal of Pharmaceutical Analysis》《临床血液学杂志》《Cellular & Molecular Immunology》《Chinese Medical Journal》更多>>; 相关基金：国家自然科学基金四川省应用基础研究计划项目美国中华医学基金国家教育部博士点基金更多>>

Analysis of the CDR3 Length Repertoire and the Diversity of TCRα Chain in Human Peripheral Blood T Lymphocytes被引量：10: 《Cellular & Molecular Immunology》2007年第3期215-220,共6页Xinsheng Yao Ying Diao Wanbang Sun Junmin Luo Ming Qin Xianying Tang; Analysis of complementarity determining region 3 （CDR3） length of T lymphocyte receptors （TCRs） by immunoscope spectratyping technique has been used successfully to investigate the diversity of TCR in autoimmune d...; 关键词：TCR GENESCAN CDR3 SPECTRATYPING immunoscope

Comparison of STR polymorphism among a Kirgiz ethnic group from Sinkiang and other groups被引量：1: 《Journal of Pharmaceutical Analysis》2007年第1期97-100,共4页高树辉李生斌; This work was supported by the National Natural Science Foundation of China(No.39940401).; Objective To study the genetic relationship between Kirgiz individuals living in Sinkiang China and analyze the difference among Kirgiz and the other population with STR polymorphisms.Methods PCR amplification was per...; 关键词：short tandem repeats(STR) KIRGIZ gene frequency GENESCAN POLYMORPHISM

STR基因座荧光标记复合扩增检测及其法医学应用被引量：2: 《法医学杂志》2005年第2期96-99,共4页李英碧吴谨侯一平张霁廖淼张林陈国弟; 四川省科技厅应用基础基金项目(03JY029-074-1);纽约中华医学基金项目(CMB;2000-636); 目的建立荧光标记复合扩增检测4个STR基因座的方法,应用于法医学亲权鉴定与个人识别。方法用6-FAM标记D3S1754引物,HEX标记D4S2366和D12S375引物,TMR标记D1S549引物,PCR复合扩增,310基因分析仪电泳自动收集电泳结果数据,GeneScanAnalysi...; 关键词：STR基因座荧光标记法医学应用检测 310基因分析仪 GENESCAN Analysis PCR复合扩增个人识别亲权鉴定分型结果基因型分型多态性研究自动收集扩增产物方法应用引物 HEX TMR 灵敏度稳定性电泳

T cell receptor Vβ repertoire usage and clonal expansion of T cells in chronic myelogenous leukemia被引量：10: 《Chinese Medical Journal》2004年第6期840-843,共4页李扬秋杨力建陈少华张玉平张学利罗更新; ThisworkwassupportedbytheNationalEducationMinistry (No 2 0 0 0 65 )andDepartmentofEducationofGuangdongProvince(No 2 0 0 0 2 1)andtheKeyProjectFoundationoftheScienceandTechnologyCommissionofGaungdongProvince(No 2KM 0 5 40 3s); Background In general,it is very important to understand the state of T cell immune response against tumor cells in leukemia patients and it is especially critical to assess the T cell repertoire of untreated patients...; 关键词：TCR Vβ gene·CML·T cell clonality·genescan

A NORTHWEST DATABASE MODEL OF SHORT TANDEM REPEAT LOCI IN FORENSIC MEDICINE被引量：1: 《Journal of Pharmaceutical Analysis》2003年第1期93-96,110,共5页王振原朱波峰刘雅诚严江伟霍振义金天博李涛樊拴良方杰; ThisworkwassupportedbytheScientificResearchItemofXi’ancity (No .2 0 0 2 3 9); Objective To establish the northwest database of short tandem repeat(STR) loci in forensic medicine. Methods Bloodstains or whole blood samples were collected from the unrelated prisoners in Xi'an city. Genetic dist...; 关键词：short tandem repeat(STR) DNA database GENESCAN polymerase chain reaction GENOTYPE

T cell receptor Vβ gene bias in rheumatoid arthritis被引量：3: 《Chinese Medical Journal》2002年第6期856-859,共4页张卓莉张国柱董怡; Objectives To explore the pathogenesis of rheumatoid arthritis (RA) by studying the expression of T cell receptors (TCRs).Methods T cell receptor Vβ (TCR Vβ) gene usage and expression were analyzed from synovial mem...; 关键词：rheumatoid arthritis · T cell receptor Vβ gene · polymerase chain reaction · genescan

GENETIC POLYMORPHISM OF STR LOCI IN CHINESE DRUNGS: 《Journal of Pharmaceutical Analysis》2002年第1期30-32,共3页赖江华郑海波朱波峰李生斌; ThesubjectwassupportedbyNationalNatureScienceFoundationofChina (No .39970 40 1); Objective To study the STR polymorphism in Chinese Drungs. Methods The genetic distributions of 15 STR loci and Amelogenin locus were generated through coamplification, genescan and genotype from 65 Drungs. Results...; 关键词：Drung nationality STR polymorphism coamplification GENESCAN

Stable clonal expansion of the T-cell receptor Vβ6, Vβ17 and Vβ19 T cells in a cGVHD case using genescan analysis: 《Chinese Medical Journal》2001年第5期41-44,105,共5页李扬秋杜欣许敏华张涛杨力建陈少华; Objective To investigate the distribution and clonality of the T-cell receptor (TCR) Vβ repertoire in chronic graft versus host disease (cGVHD).Methods The complementarity determining region 3 (CDR3) of the TCRβ gen...; 关键词：TCR V β gene · genescan · T cell clonality · graft versus host disease

ANALYSIS OF T CELL CLONALITY BY CDR3 SIZE OF T-CELL ANTIGEN RECEPTOR Vβ REPERTOIRE IN HCL AND c-ALL: 《Chinese Journal of Cancer Research》1999年第3期196-199,共4页李扬秋汪明春 SiegertW SchmadtCA; Objective: To analyze the distribution and clonality of TCR Vβ subfamily T cells in hairy cell leukemia (HCL) and common-acute lymphoblastic leukemia (c-ALL). Methods: Peripheral blood mononuclear cell samples from 3...; 关键词：T cell receptor Vβ CDR3 leukemia T cell clonality GENESCAN

用RT-PCR和Genescan分析CML急变期病人TCRVβT细胞的表达和克隆性被引量：8: 《临床血液学杂志》1998年第3期98-100,共3页李扬秋杜欣汪明春廖继东; 目的：了解CML急变期的TCRVβ亚家族T细胞的表达及其克隆性。方法：采用RT－PCR扩增4例CML急变期病人的外周血单个核细胞的TCRVβ24个亚家族的互补决定区3（CDR3），产物进一步经基因扫描分析确定T细胞的克隆性。结果：病人外周血仅表达...; 关键词：TCRVΒ基因基因扫描 T细胞克隆性 CML急变期

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