云南红河哈伲、奕族人群中异常血红蛋白的调查研究  

Screening of Abnormal Hemoglobin Among People of Hani and Yi Minority Nationalities in Honghe Yunnan

作　　者：宋文凤 邱志明[1] 李庆军 段勇[1] 汪晓英[1] 

机构地区：[1]昆明医学院生化教研室

出　　处：《昆明医科大学学报》1993年第4期24-26,共3页Journal of Kunming Medical University

基　　金：国家自然科学基金

摘　　要：本文报道对云南红河哈伲及奕等少数民族进行异常Hb的调查研究。通过筛选调查,查明受检地区人群中异常Hb的发生率为1.25％。并经异常Hb变异类型鉴定研究,确证在哈伲及奕族人群中存在的异常Hb其类型主要为HbE。另外发现1例G组慢速Hb,经一级结构分析证实为β变异,命名为Hb G-Yuanyang(β43(CD2)Glu→Gly)。它是在云南省首次发现及报道的一种新型异常Hb。The resuets of the screening of abnormal Hb among people of Hani and Yi minority nationalitios in Honghe, Yunnan were reported in this paper, It was found that the inci- dence of abnormal Hb in This area was 1.25%, By studying the types of abnormal Hb, we found that the main abnormal Hb in Hani and Yi minority nationalities was Hb E. In addi- tion, a slow-mouing Hb was found, Primary structural analysis showed that it was a β-Chaim variant designated as Hb G-Yuanyang (β43 (CD2) Glu-Gly),. it is a new vari- ant type of abnormal Hb found and reported for the first time in Yunnan, China.

关 键 词：少数民族 异常Hb 变异类型 

分 类 号：R[医药卫生]