多不饱和脂肪酸在癌症及炎症疾病方面的研究进展  

Research advances of polyunsaturated fatty acids in cancer and inflammation disease

作　　者：郎丽巍[1] 王洪允[1] 胡蓓[1] 江骥[1] 

机构地区：[1]中国医学科学院北京协和医学院北京协和医院临床药理研究中心,北京100730

出　　处：《中国生化药物杂志》2014年第1期153-155,158,共4页Chinese Journal of Biochemical Pharmaceutics

摘　　要：n—3和n—6多不饱和脂肪酸是必需脂肪酸,对于人类的健康是必要的。目前,饮食的结构中多为高含量的n—6多不饱和脂肪酸且n—3多不饱和脂肪酸含量偏低,由此产生n—6/n—3比例失衡,有可能导致心血管疾病、炎症、和癌症等疾病的产生。本文从多不饱和脂肪酸的摄取及代谢转化方面阐述其对于癌症及炎症疾病产生的影响,同时也对其作用机制和临床研究进展进行了探讨。N-3 and n-6 unsaturated fatty acids are essential fatty acids. It is necessary for human health. At present, the diet contains a disproportionally high amount of n-6 PUFAs and low amount of n-3 PUFAs, and the resulting high n-6/n-3 ratio is thought to contribute to cardiovascular disease, inflammation, and cancer. This article is about the polyunsaturated fatty acid uptake and metabolism in its study on the impact of progress in cancer and inflammatory diseases and its mechanism of action and clinical research.

关 键 词：多不饱和脂肪酸 癌症 炎症 

分 类 号：R979.9[医药卫生—药品]