乳酸及腹腔内压变化与腹腔高压综合征病情及预后的关系  

Relationship of lactic acid and intra-abdominal pressure changes with the condition and prognosis of abdominal compartment syndrome

作　　者：李秀宪[1] 李文耀[1] 

机构地区：[1]菏泽市立医院,山东菏泽274000

出　　处：《山东医药》2013年第37期31-33,共3页Shandong Medical Journal

摘　　要：目的探讨乳酸及腹腔内压变化与腹腔高压综合征患者病情及预后的相关性。方法根据45例患者入院时血清乳酸、腹腔内压(IAP)分为代偿性酸中毒组,乳酸性酸中毒组;IAP≤20 mmHg组,IAP>20 mmHg组,观察心率、血压、呼吸频率、吸气压峰值、动脉血氧分压和尿量等检测指标。结果乳酸性酸中毒组、代偿性酸中毒组病死率分别为31.3%、6.9%,治疗前后各监测指标比较,P均<0.01;IAP>20 mmHg组、IAP≤20 mmHg组病死率分别为35.7%、6.5%,治疗前后各监测指标比较,P均<0.01。结论血清乳酸及腹腔内压监测在判断病情变化、严重程度、治疗方式的选择和预后方面有着非常重要的意义。Objective To investigate the correlation of lactic acid and intra-abdominal pressure( IAP) changes with the condition and prognosis of patients with abdominal compartment syndrome. Methods According to the lactic acid and IAP,45 patients were divided into the compensated acidosis group,lactic acidosis group; IAP≤20 mmHg group and IAP > 20 mmHg group,respectively. The changes of lactic acid and IAP were detected,and heart rate,blood pressure, breathing rate,peak inspiratory pressure,arterial partial pressure of oxygen and urine volume were observed. Results The mortality rates in the lactic acidosis and compensated acidosis groups were respectively 31. 3% and 6. 9%; the mortality rates in the IAP > 20 mmHg and IAP≤20 mmHg groups were separately 35. 7% and 6. 5%; and the comparison of monitoring indexes before and after treatment was significant( all P < 0. 01) Conclusion Lactic acid and intra-abdominal pressure monitoring has a very important significance in judging the condition changes and severity,early intervention of different treatment and prognosis.

关 键 词：腹腔高压综合征 乳酸 腹腔内压 预后 关系 

分 类 号：R572[医药卫生—消化系统]