Study on biomechanical mechanism of bone remodeling  

作　　者：Xizheng Zhang 

机构地区：[1]Institute of Medical Equipment,Academy of Military Medical Sciences

出　　处：《医用生物力学》2013年第S1期93-94,共2页Journal of Medical Biomechanics

基　　金：supported by the National Natural Science Foundation of China(No.10832012)

摘　　要：Background Bone is a dynamic tissue that constantly undergoes remodeling in which a coupled process of bone formation and resorption continues throughout life.This remodeling is necessary to maintain the structural integrity of the skeleton under conditions of changing mechanical forces.It is important to develop bone remodeling theory in order to explain bone development and to instruct bone disease therapy and rehabilitation.However,the process and mechanism are not fully understood.Our study was carried out to investigate biomechanical mechanism of bone remodeling with the respect to bone tissue/cell mechanobiology,computational biomechanics and animal model.Background Bone is a dynamic tissue that constantly undergoes remodeling in which a coupled process of bone formation and resorption continues throughout life.This remodeling is necessary to maintain the structural integrity of the skeleton under conditions of changing mechanical forces.It is important to develop bone remodeling theory in order to explain bone development and to instruct bone disease therapy and rehabilitation.However,the process and mechanism are not fully understood.Our study was carried out to investigate biomechanical mechanism of bone remodeling with the respect to bone tissue/cell mechanobiology,computational biomechanics and animal model.

关 键 词：REMODELING rehabilitation constantly MAINTAIN understood SCAFFOLD SKELETON EXPLAIN integrity INTERMITTENT 

分 类 号：R318.01[医药卫生—生物医学工程]