Photodynamic therapy for high-grade dysplasia of bile duct via a choledochoscope  

作　　者：Jiang-Jiao Zhou Li Xiong Qing-Long Li Ying Gu Yu Wen Xiao-Feng Deng Xiong-Ying Miao 

机构地区：[1]Department of General Surgery,the Second Xiangya Hospital,Central South University [2]Department of Laser Medicine,301 Hospital

出　　处：《World Journal of Gastroenterology》2013年第33期5590-5592,共3页世界胃肠病学杂志（英文版）

摘　　要：When a distal common bile duct neoplasm is at the stage of carcinoma in situ or high-grade dysplasia,it is difficult for the surgeon to decide whether to perform pancreaticoduodenectomy.Here we describe a patient with a progressive dysplastic lesion in the common bile duct,which developed from moderate-high to highgrade dysplasia in approximately 2 mo.The patient refused major surgery.Therefore,endoscopic-assisted photodynamic therapy was performed.The result at follow-up using a trans-T-tube choledochoscope showed that the lesion was completely necrotic.This report is the first to describe the successful treatment of highgrade dysplasia of the distal bile duct using photodynamic therapy via a choledochoscope.When a distal common bile duct neoplasm is at the stage of carcinoma in situ or high-grade dysplasia, it is difficult for the surgeon to decide whether to perform pancreaticoduodenectomy. Here we describe a patient with a progressive dysplastic lesion in the common bile duct, which developed from moderate-high to high-grade dysplasia in approximately 2 mo. The patient refused major surgery. Therefore, endoscopic-assisted photodynamic therapy was performed. The result at follow-up using a trans-T-tube choledochoscope showed that the lesion was completely necrotic. This report is the first to describe the successful treatment of high-grade dysplasia of the distal bile duct using photodynamic therapy via a choledochoscope.

关 键 词：Photodynamic therapy COMMON BILE DUCT HIGH-GRADE DYSPLASIA CHOLEDOCHOSCOPE 

分 类 号：R735.8[医药卫生—肿瘤]