The relationship between the hepatitis B virus base core and precore/core promoter mutations and the development of cirrhotic hepatocellular carcinoma and noncirrhotic hepatocellular carcinoma  

作　　者：徐尧江 

机构地区：[1]Dept Infect Dis,People's Hosp

出　　处：《China Medical Abstracts(Internal Medicine)》2013年第1期13-13,共1页中国医学文摘（内科学分册（英文版）

摘　　要：Objective To investigate the mutations of basal core promoter(BCP) and precore(PreC) region of hepatitis B virus(HBV) and the association with the development of hepatocellular carcinoma in patients with chronic HBV infection. Methods Totally 381 untreated HBV patients were recruited from the Department of

关 键 词：cirrhotic promoter UNTREATED BASAL independently mutation GENOTYPE sequencing 

分 类 号：R735.7[医药卫生—肿瘤]