基于Matlab/Simulink的青霉素发酵过程仿真平台  

Simulator of Penicillin Fermentation Process in Matlab/Simulink Environment

作　　者：叶凌箭[1,2] 程江华 

机构地区：[1]浙江大学控制科学与工程学系,杭州310027 [2]浙江大学宁波理工学院,宁波315100 [3]中国联合工程公司,杭州310022

出　　处：《系统仿真学报》2015年第3期515-520,共6页Journal of System Simulation

基　　金：国家自然科学基金项目(61304081);浙江省自然科学基金资助项目(LQ13F030007);中国博士后科学基金(2013M541778)

摘　　要：对青霉素发酵过程进行控制和优化研究,需要开发适用的仿真平台。当前国际上较有影响力的仿真平台Pen Sim,只能在指定操作条件下产生用于分析的过程数据,不适用于青霉素发酵过程的实时控制和产量优化。对Pen Sim仿真平台的内在模型进行了深入细致的研究,基于Matlab/Simulink环境开发了新的青霉素发酵过程仿真平台。该仿真平台具有和Pen Sim高度一致的动力学特性,并且可由用户自定义操作变量轨迹(如底物流加速率),适用于对青霉素发酵过程进行控制和优化方面的研究。For control and optimization of penicillin fermentation process, a suitable simulator should be developed. Pen Sim is a world-wide famous simulator for penicillin process, however, it can only generate process data for the purpose of analysis, but not applicable for the real-time control and production optimization. The internal models in Pensim were comprehensively investigated and a new penicillin fermentation simulator was developed in the environment of Matlab/Simulink. The simulator preserves highly kinetic identity with Pensim, yet allowing users to freely define the trajectories of control variables during operation(e.g. the feed rate of substrate), thus suitable for the study of control and optimization for the penicillin fermentation process.

关 键 词：青霉素 发酵过程 模型仿真 控制与优化 

分 类 号：TQ927[轻工技术与工程—发酵工程] TP391.9[自动化与计算机技术—计算机应用技术]