常德地区1627例精神分裂症调查与分析  

Survey and analysis of 1627 schizophrenias in Changde area

作　　者：涂冰[1] 熊昌本[1] 柳小年[1] 曾孟兰[1] 周海斌 王用民[1] 黄俊 

机构地区：[1]湖南常德职业技术学院医学基础部,415000 [2]湖南省常德市康复医院

出　　处：《中国优生与遗传杂志》2004年第3期126-127,119,共3页Chinese Journal of Birth Health & Heredity

基　　金：常德市科研项目 (0 3 -0 9-18)

摘　　要：目的　为精神分裂症的预防提供参考依据。方法　对常德市康复医院精神分裂症住院患者进行回顾性研究。结果　 16 2 7例患者中 ,男女之比为 1∶1.2 4。≤ 15岁男女平均始发年龄差异无显著性 ,男女始发年龄差异有显著性是在 15岁之后 ,女性发病迟于男性。农村患者约占 2 / 3。儿童少年患者占 1 91%。先证者一、二级亲属患病率差异具非常显著性。先证者同胞患病率 ,双亲正常的为 6 71% ;双亲之一受累的为 16 0 5 %。结论　先证者亲属的患病率可作为经验风险供遗传咨询参考。精神分裂症预防的重点应放在早期发现、早期治疗和预防复发上。Objective: The aim is for the prevention of schizophrenia. Methods: The review research was on the patients with schizophrenia who were in Changde rehabilitation hospital. Results: In 1627 cases male to female is in the ratio of 1∶1.24. In≤15 years old girls and boys the difference of average onset ages between them is no significant. The difference of onset ages between male and female are significant after 15 years old. The female are more lately than male. The cases from country are roughly 2/3. Young patients of child are 1·91%.The difference of morbidity between the proband's first-degree and second-degree relatives is very significant. The morbidity of proband's compatriot whose parents are normal is 6.71%;that one of whose parents are not normal is 16·05%. Conclusions: The morbidity of the proband's relatives can be used as the experience risk in the genetic counseling. The prevention for schizophrenia is better than cure and should be put on the earlier period.

关 键 词：精神分裂症 始发年龄 先证者 家族史 患病率 

分 类 号：R749.3[医药卫生—神经病学与精神病学]