分化型甲状腺癌患者的^(131)I-SPECT/CT断层融合显像  

^(131)I-SPECT/CT in management of patients with differentiated thyroid carcinoma

作　　者：陈立波[1] 罗全勇[1] 余永利[1] 金常青[1] 于建芳[1] 陆汉魁[1] 朱瑞森[1] 沈艳[2] 

机构地区：[1]上海交通大学附属第六人民医院核医学科,上海200233 [2]上海交通大学附属第六人民医院放射科,上海200233

出　　处：《中国医学影像技术》2004年第7期1111-1113,共3页Chinese Journal of Medical Imaging Technology

基　　金：上海市科技发展基金项目 (0 2 4 1 1 90 53)

摘　　要：目的　探讨13 1I SPECT/CT在分化型甲状腺癌 (DTC)诊断中的可行性及其定性与定位诊断价值。方法　对 43例手术 + 13 1I治疗后DTC患者 ,行13 1I WBS及13 1I SPECT/CT显像 ,并观察13 1I浓聚灶在CT图像上的位置。对两种显像结果皆为阴性者做作18F FDG符合显像。结果　13 1I SPECT/CT较13 1I WBS具有更高的阳性率 ,并排除 11处13 1I WBS假阳性病灶。结论　对DTC进行 13 1I SPECT/CT断层融合显像 ,在提供更多有关对甲状腺癌病灶的摄碘信息的同时 ,提高了对病灶的定位诊断能力 。Objective To evaluate the feasibility and the capability of 131 I -SPECT/CT in detecting lesions of differentiated thyroid carcinoma. Methods Forty-three patients with differentiated thyroid carcinoma in all were selected to underwent 131 I-WBS and 131 I-SPECT/CT after operation and 131 I therapy. 131 I uptake sites were observed in 131 I-SPECT/CT images. 18 F-FDG CoDe was added if both 131 I-WBS and 131 I-SPECT/CT presented negative results. Results 131 I-SPECT/CT showed a higher positive rate than that of 131 I-WBS. Eleven false positive lesions were excluded and all localizations were made by 131 I-SPECT/CT. Conclusion 131 I-SPECT/CT is a very useful method in detecting lesions of differentiated thyroid carcinoma. This method can provide more information about 131 I uptake and locations of lesions, as is vital to modulating therapeutic plans and making follow-up schemes.

关 键 词：体层摄影术 单光子发射计算机断层 甲状腺癌 图像融合 

分 类 号：R736.1[医药卫生—肿瘤] R814.42[医药卫生—临床医学]