猪肝门静脉生物力学特性的增龄性变化  

THE MECHANICAL PROPERTIES OF HEPATIC PORTAL VEIN IN PIGS WITH AGING

作　　者：王配军[1] 李文春[1] 唐杰[1] 陈家强[1] 张一飞[1] 黄铁柱[1] 

机构地区：[1]郧阳医学院解剖教研室,湖北十堰442000

出　　处：《医用生物力学》2003年第4期218-221,共4页Journal of Medical Biomechanics

基　　金：湖北省教育厅科研资助项目 (No .2 0 0 3z0 0 1)

摘　　要：目的　研究猪肝门静脉的生物力学特性与月龄间的关系 ,为猪→人异种肝移植提供力学资料。方法　取不同月龄猪肝门静脉 ,利用软组织力学试验机测量压力 -直径关系数据 ,推导出其弹性模量和顺应性。结果　猪肝门静脉的弹性模量随猪的月龄的增大和血管内压力的升高而增大 ;顺应性则随猪的月龄的增大而下降。结论　猪肝门静脉的力学特性随增龄发生变化 ,在实施猪→人异种肝移植时应选择与人肝门静脉力学特性相匹配的月龄猪作为供体。Objective To investigate the changes of the mechaniccal properties of hepatic portal vein in the pig with various ages and to provide mechanical data for pig-to-human liver xenotransplantation.Methods The hepatic portal vein of different ages of pig were used to conduct mechanical experiment, and the data of Pressure and Diameter was measuted to calculate the elastic modulus and compliance.Results The elastic modulus of hepatic portal vein of pig incresaed with aging and pressute in vessel, while the compliance descended with aging.Conclusion The mechanical properties of hepatic portal vein of pig change with aging, the pig matched the mechanical property of hepatic portal vein of human should be chosen for liver xenotransplantation.

关 键 词：肝门静脉 生物力学 猪 异种移植 

分 类 号：R318.01[医药卫生—生物医学工程]