神经纤维瘤病的颅脑和脊柱的MRI表现  

MRI Findings of Neurofibromatosis in Cranium and Spinal Column

作　　者：李玉华[1] 张永平[1] 薛建平[1] 朱礼华[1] 

机构地区：[1]上海第二医科大学附属新华医院放射科,上海200092

出　　处：《中国医学影像技术》2003年第6期745-747,共3页Chinese Journal of Medical Imaging Technology

摘　　要：目的　认识神经纤维瘤病的颅脑及脊柱MRI表现 ,为临床进一步诊治提供客观依据。方法　回顾性分析 16例临床或影像学确诊神经纤维瘤病患者的MRI图像 ,同时查阅了近年国内外相关研究资料 ,提出神经纤维瘤病的主要颅脑和脊柱的MRI表现及有关病理解释。结果　 11例为NF1,5例为NF2 ,NF1中眼眶周围丛状神经纤维瘤 6例 ,其中 5例伴蝶骨翼发育不良 ,视神经增粗 1例 ,基底节信号异常 8例 ,2例伴椎管神经纤维瘤。NF2均表现为两侧听神经瘤 ,其中 2例合并多发脑膜瘤及其他颅神经瘤和椎管肿瘤。结论　NF1及NF2有明显特征性颅脑及脊柱影像学表现 ,结合临床及影像资料 ,我们能对神经纤维瘤病对颅脑及脊柱影响作出客观的评价。Objective To understand MRI findings of neurofibromatosis in cranium and spinal column is helpful in providing reliable informations for further clinical management. Methods Sixteen cases of neurofibromatosis were reviewed retrospectively, which were confirmed by clinical criteria in NF1 or by MRI study in NF2.Combined with published papers recent years,main MRI features of NF1 or NF2 were proposed and correlated pathology were also discussed. Results Eleven cases were NF1,5 cases were NF2. Among the NF1,6 cases associated with plexiform neurofibromatosis,they all occurred in periorbital regions and 5 cases associated with dysplasia of sphenoid wing.One case showed thickening of optical nerve. Abnormal signal intensity occurred in basal ganglia areas in 8 cases.Two cases also associated with spinal canal neurofibromas. Among NF2,bilateral the eighth cranial nerve schwannomas were seen in all cases,2 cases associated with multiple meningiomas,other cranial nerve tumors and spinal canal tumors. Conclusion The image findings of NF1 and NF2 in the cranium and spinal column are specific based on the clinical materials and MRI findings, we can evaluate the involvement of neurofibromatosis in both cranium and spinal column correctly. [

关 键 词：颅脑 神经纤维瘤病 脊柱 MRI表现 NF2 临床 多发 合并 国内外 客观依据 

分 类 号：R739[医药卫生—肿瘤] R730[医药卫生—临床医学]