我国瑶、汉、壮、苗、维五个民族补体成份B因子多态性的调查报告  

GENETIC POLYMORPHISM OF THE COMPLEMENT COMPONENT FACTOR B (BF) IN YAO, HAN, ZHUANG, MIAO AND UIGUR NATIONALITIES IN CHINA

作　　者：翦必希 赵修竹[1] 程健华[1] 洪涛[1] 田廷武 江策[1] 吴雄文[1] 朱作金[2] 张明安 尹经正 黄莲宝 郭炯[4] 

机构地区：[1]武汉同济医科大学病理生理学教研室中澳友谊补体实验室 [2]广西医学院病理生理学教研室 [3]新疆喀什卫校 [4]新疆医学院病理生理学教研室

出　　处：《人类学学报》1989年第3期269-273,共5页Acta Anthropologica Sinica

基　　金：国家自然科学基金

摘　　要：用琼脂糖凝胶高压电泳及免疫固定技术对我国瑶、汉、壮、苗、维五个民族人群的补体B因子(Bf)的多态性进行了检测,结果显示,这五个民族的Bf基因频率均以s型最高,但参差不齐。从高到低的顺序是瑶0.9071,汉0.8727,壮0.8426,苗0.7667,维0.6622。BfF基因频率其次,但也高低不一,从高到低的顺序是维0.2680,苗0.2000,壮0.1343,汉0.1159,瑶0.0929。频率居第三位的是BfSO7,差别显著,维0.0586,苗0.0333,壮0.0232,汉0.0091,瑶0.0000。在罕见型方面,220例份汉族人中发现一例SO45杂合子,222例份维族中检出4例FO65及1例F1杂合子。本文结合我国其他民族及全球大量检测数据进行了一些对比讨论。The complement component factor B (Bf) polymorphism of Yao, Han, Zhuang, Miao and Uigur in China was investigated by means of high voltage agarose gel electrophoresis and seb-sequent immunofixation. The results showed that the Bf*S gene frequencies were the highest in all five ethnic groups. These were Yao 0.9071, Han 0.8727, Zhuang 0.8426, Miao 0.7667, and Uigur 0.6622, respectively. The Bf*F was the second major gene in these ethnic groups: Ulgur 0.2680, Miao 0.2000, Zhuang 0.1343, Han 0.1159 and Yao 0.0929, respectively. The Bf SO7 was the less common gene: Uigur 0.0586, Miao 0.0333, Zhuang 0.0231, Han 0.0091, and Yao 0.0000, respectively. In addition, some rare phenotypes were found, such as SO 45 in Han and FO 65 and F 1 in Uigur.

关 键 词：补体 B因子 人类遗传学 

分 类 号：Q987[生物学—遗传学]