Z_5-G菌生产聚β-羟基丁酸发酵动力学模型  

Dynamic models for poly-β-hydroxybutyrate fermentation process

作　　者：黄建新[1] 杨金水[2] 卫阳[1] 

机构地区：[1]西北大学陕西省生物技术重点实验室,陕西西安710069 [2]中国农业大学生物学院,北京100094

出　　处：《化学工程》2005年第1期44-47,共4页Chemical Engineering(China)

基　　金：国家'863'计划新材料领域资助项目(715 004 0160)

摘　　要：研究了Z5 G菌株在 3L搅拌发酵罐中以蔗糖为碳源分批发酵生产聚β 羟基丁酸 (PHB)的生长特性。在Lo gistic方程和Luedeking Piret方程的基础上,建立了Z5 G菌发酵过程中菌体生长、基质消耗、产物形成的动力学模型。应用MathCAD软件处理实验数据和模型,拟合出所有模型参数,建立了动力学模型,经过验证模型预测值和实验值吻合较好,表明此动力学模型对指导PHB的发酵生产具有实际意义。The growth characteristic of batch producing poly-β-hydroxybutyrate (PHB)of Z_5-G bacteria in 3 L (agitated) fermentation cylinder with sucrose as carbon source was studied. On the basis of Logistic equation and (Luedeking)-Piret equation, the dynamic models were established, involving cell growing, substrate consumption and product formation during Z_5-G bacteria fermentation process. The parameters of the models were established by (using) MathCAD software with experimental data and the models. It shows that the predict values of the models and experimental data are in a good agreement, and the models are important for guiding fermentation producing of PHB.

关 键 词：聚β—羟基丁酸(PHB) 发酵 动力学模型 

分 类 号：TQ920.1[轻工技术与工程—发酵工程]