脑血栓患者血清β-胡萝卜素和维生素E与脂质过氧化的关系探讨  

Serum β-carotene vitamin E and malonic dialdehyde in patients with cerebral thrombosis

作　　者：谭兰[1] 韩仲岩[1] 冠良全 林利平[3] 吴晖云[3] 

机构地区：[1]青岛医学院附属医院,266003 [2]巨野县人民医院 [3]青岛医学院营养系

出　　处：《临床神经病学杂志》1994年第1期20-21,共2页Journal of Clinical Neurology

摘　　要：本文测定了４６例脑血栓病人，１８例ＴＩＡ病人及１９例健康老年人的血清丙二醛（ＭＤＡ），β－胡萝卜素（β－Ｃ）和维生素Ｅ（Ｖ－Ｅ）水平。结果显示：急性期脑血栓病人及ＴＩＡ病人的血清ＭＤＡ水乎高于对照组，有统计学意义；Ｖ－Ｅ水平则差别无统计学意义。本结果说明缺血性脑血管病患者β－Ｃ的消耗有增加趋势，可能与脑血栓病人血清ＭＤＡ水平上升，脑损伤加重有关。而Ｖ－Ｅ抗脂质过氧化作用不明显，可能与混杂因素有关。Serum concentrations of malonic dialdehyde (M-DA),β-carotene (β-C)and vitamin E (VE) were measured in 19 normal subjects, 46 patients with cerebral thrombosis and 18 patients with transient ischemic attack (TIA). Results showed that in the group of cerebral thrombosis the level of serum MDA was significantly elevated (P<0. 01 ), and the level of serum β-C was significantly low when compared with controls (P<0. 05). In the group of TIA the level of serum MDA was significantly elevated (P<O. 05),and the level of serum β-C was significantly low (P<0. 05). Serum VE was not significantly changed among the three groups. The results indicated that there was an increasing β-C consumption in patients with ischemic cerebral vascular diseases, which may be due to elevated serum MDA and cerebral injuries. Increased anti-lipid-peroxidation of VE was not obvious,which may be due to various factors.

关 键 词：脑血栓 丙二醛 胡萝卜素 维生素 

分 类 号：R743.320.2[医药卫生—神经病学与精神病学]