声动力学疗法的研究进展  

Development of sonodynamic therapy

作　　者：刘全宏[1] 吴二林[1] 王攀[1] 

机构地区：[1]陕西师范大学生命科学学院,陕西西安710062

出　　处：《陕西师范大学学报（自然科学版）》2005年第1期120-124,共5页Journal of Shaanxi Normal University：Natural Science Edition

基　　金：国家自然科学基金重点资助项目(39870240;30270383)

摘　　要：在综合国内外文献的基础上,就声动力学疗法在离体、在体的实验研究状况、光敏剂的选择及与其他抗肿瘤方法的联合应用做了阐述,并对其作用机制进行了总结,指出该疗法的抗肿瘤机制是多因素协同作用的结果.同时对声动力学疗法目前研究中存在的问题及发展前景进行了预测和评述.Sonodynamic therapy (SDT) is a new method of tumor treatment. A review of current knowledge concerning on the development of in vitro and in vivo experimental research, photosensitizers of SDT, the synergistic effect between SDT and other treatments is presented. The summary of mechanism of SDT is described, the mechanism of SDT is probably not governed by universal mechanism, but maybe influenced by multiple factors. The future development prospect and the existing problem of the studying in this field are discussed.

关 键 词：声动力学疗法 抗肿瘤机制 研究进展 联合应用 离体 作用机制 实验研究 国内外 发展前景 状况 

分 类 号：R730[医药卫生—肿瘤]