CT灌注成像在肾肿瘤鉴别诊断中的应用价值  

Value of CT perfusion imaging in diagnosis of renal tumors

作　　者：袁庆中[1] 田建明[1] 王培军[1] 邵成伟[1] 李树平[1] 李跃华[1] 任方远[1] 

机构地区：[1]上海长海医院放射科,上海200433

出　　处：《中国医学影像技术》2005年第3期436-439,共4页Chinese Journal of Medical Imaging Technology

摘　　要：目的　探讨CT灌注成像在肾肿瘤定性诊断和鉴别诊断方面的应用价值。方法　共收集肾癌 15 例,肾盂癌 9例,肾错构瘤12例。以健康志愿者30例为对照组。进行肾区CT平描后选择经肾门层面或肿瘤的最大层面进行同层动态增强扫描,通过感兴趣区域分析法获得正常肾皮质、肾肿瘤组织和腹主动脉的时间 密度曲线,计算正常肾皮质和肾肿瘤组织的灌注值。结果　正常肾皮质的灌注值为(2.68±0.40) ml/(min·ml),肾癌灌注值为(1.51±0.68) ml/(min·ml),肾癌灌注值显著高于肾盂癌和肾错构瘤的灌注值。结论　CT灌注成像在肾肿瘤定性诊断和鉴别诊断方面具有一定的临床应用价值。Objective To discuss the value of CT perfusion imaging in diagnosis of renal tumors. Methods By applying a nuclear medicine data processing technique to the time-density data obtained from dynamic CT, perfusion was performed in 30 cases of nomal renal cortex and 36 cases of renal tumors, including 15 cases of renal cell carcinoma (RCC), 9 cases of renal pelvic carcinoma (RPC), 12 cases of renal agiomyolipoma (RAML). A single level through the renal hili or renal tumor was scanned after the intravenous injection of 40-50 ml of contrast given at 5 ml/s. Thirty 0.5 s duration and 0.5 s interval scans were performed from 8 to 37 s after injection. Time-density curves were then drawn for both normal kidneys or renal tumor and aorta using regions of interest (ROIs). Perfusion was calculated as the peak upslope of the tissue time-density curve divided by peak aortic enhancement. Results Normal renal cortal perfusion was (2.68±0.40) ml/(min·ml). Perfusion of RCC, RPC and RAML were (1.51±0.68) ml/(min·ml),(0.80±0.11) ml/(min·ml) and (0.96±0.33) ml/(min·ml) respectively. Perfusion of RCC was much higher than that of other two renal tumors. Conclusion There is some value of CT perfusion imaging in diagnosis of renal tumors.

关 键 词：体层摄影术 X线计算机 灌注成像 肾脏 肾脏肿瘤 

分 类 号：R737.11[医药卫生—肿瘤] R814.42[医药卫生—临床医学]