New Asymmetric Synthesis of Alkannin and Shikonin  

作　　者：JianGangZHANC QunLU WenHuDUAN JunCaoCAI 

机构地区：[1]ShanghaiInstituteofMateriaMedica,ShanghaiInstitutesforBiologicalSciences,GraduateSchooloftheChineseAcademyofScienceChineseAcademyofSciences,,Shanghai201203

出　　处：《Chinese Chemical Letters》2005年第4期465-467,共3页中国化学快报（英文版）

基　　金：the National Natural Science Foundation of China[32071532]for financial supports

摘　　要：A new approach for asymmetric synthesis of alkannin and shikonin is presented. The chiral centers of the targets were introduced via an asymmetric C-arylation of protected chiral glyceraldehyde in high de. The two enantiomers were prepared with the D-isopropylidenegly- ceraldehyde as the starting material.A new approach for asymmetric synthesis of alkannin and shikonin is presented. The chiral centers of the targets were introduced via an asymmetric C-arylation of protected chiral glyceraldehyde in high de. The two enantiomers were prepared with the D-isopropylidenegly- ceraldehyde as the starting material.

关 键 词：Asymmetric synthesis ALKANNIN SHIKONIN arylglycerols. 

分 类 号：R917[医药卫生—药物分析学]