原花青素对亚硝化反应的抑制作用研究  

Study on Inhibition of Nitrosation by Procyanidins

作　　者：吴春[1] 代丽君[2] 聂芊[1] 

机构地区：[1]哈尔滨商业大学化学中心,哈尔滨150076 [2]哈尔滨商业大学商品学系,哈尔滨150076

出　　处：《天然产物研究与开发》2005年第2期213-216,共4页Natural Product Research and Development

基　　金：哈尔滨市科技局基金项目 (2 0 0 2AFXXJ0 3 0 );黑龙江省教育厅骨干教师项目 (10 5 2G0 5 8)

摘　　要：研究了葡萄籽原花青素的最佳提取条件,及其对亚硝化反应的抑制作用。结果表明:原花青素的最佳提取条件为6 0 %乙醇,料液比1∶5 ,5 0℃水浴回流1h ,其对亚硝胺合成的最大阻断率为91.2 % ,对亚硝酸钠的最大清除率为88.3%The optimun extraction conditions of procyanidins from defatted grape seads and the inhibition of nitrosation were studied.The results showed that the optimun extraction conditions were extracting procyanidins with 60% alcohol solution in a water bath at 50 ℃ for one hour and the ratio of solid to solution is 1∶5.The maximum capabilities of inhibiting the production of nitrosamine and scavenging sodium nitrite were 91.2% and 88.3%.

关 键 词：原花青素 亚硝化反应 抑制作用 葡萄籽 提取 亚硝胺 亚硝酸钠 肿瘤 

分 类 号：R730.1[医药卫生—肿瘤] Q949.756.3[医药卫生—临床医学]