具抗真菌活性的海洋霉菌的筛选和初步研究  

Screening of Marine Mold Activity and Having Antifungi Primary Research

作　　者：李淑彬[1] 陆广欣[1] 林如妹[1] 邬进杰[1] 蔡文德[1] 

机构地区：[1]华南师范大学生命科学学院,广州510631

出　　处：《微生物学通报》2005年第2期78-82,共5页Microbiology China

基　　金：国家自然科学基金资助项目(No.30270021)

摘　　要：从中国南海海底沉积物与海水样品中分离出100多株海洋霉菌;以条件性致病真菌白色假丝酵母(Candidaalbicans),植物病原真菌镰刀菌(Fursariumsp.)等作为敏感测试菌株,初筛分离到30多株对上述测试真菌具有明显抑制作用的海洋霉菌;对其发酵液进行复筛,发现其中编号分别为B4#-6、B4#3-、1B-66、1B6-105、1-B6-22、C2#5、A29和1B6-10的海洋霉菌菌株其代谢产物粗提物有明显抗真菌活性;其抗真菌谱的实验结果表明菌株1-B6105和B4#-3的代谢产物还能抑制多种其他真菌的生长,这二个菌株具有良好的开发前景。More than one hundred strains of marine molds have been isolated from the sediment and the sample of seawater collected from the South China Sea. By the first screening, more than 30 strains of marine molds which can inhibit tested fungi such as Candida albicans and Fursarium sp. were obtained.The results of the second screening showed those strains designed as B 4#-6、B 4#-3、1-B 6-6、1-B 6-10-5、1-B 6-22、C 2#-5、A 2-9 and 1-B 6-10 can produced extracelluar antifungi metabolic products and the crude extract of the strains 1-B 6-10-5 and B 4#-3 can inhibit the growth of many other species of fungi.

关 键 词：中国南海 海洋霉菌 抗真菌作用 

分 类 号：Q939.99[生物学—微生物学]