Clinical Analysis of Xerostomia in Patients with Nasopharyngeal Carcinoma after Radiation Therapy  

鼻咽癌放疗后口干燥症的临床分析(英文)

作　　者：刘学奎[1] 曾宗渊[1] 洪明晃[1] 张爱兰[1] 崔念基[1] 陈福进[1] 

机构地区：[1]广州中山大学肿瘤防治中心头颈科,510060

出　　处：《The Chinese-German Journal of Clinical Oncology》2005年第3期137-140,187,共5页中德临床肿瘤学杂志（英文版）

摘　　要：Objective: To investigate the severity of xerostomia and its impact on the quality of life in patients with nasopharyngeal carcinoma after conventional radiation therapy. Methods: One hundred and thirty-six patients with nasopharyngeal carcinoma, treated by conventional radiation therapy in Cancer Center, Sun Yat-sen University, were surveyed by interview at the outpatient department. A questionnaire and a visual analog scale (VAS) were used to analyze xerostomia and xerostomia-related problems. Results: Of 136 patints, 73.5% experienced a moderate to severe degree of xerostomia; 82.4% had to sip water to facilitate speech; 92.6% had to sip water to facilitate chewing and swallowing; 91.2% changed their feeding pattern (eating only mashed food); 61.3% had to wake up to drink water because of dry mouth; 75.0% had dental lesions to varying degrees. Conclusion: 73.5% of the patients with nasopharyngeal carcinoma after conventional radiation therapy experienced a moderate to severe degree of xerostomia. Xerostomia has a significant impact on the patient's speech, deglutition, and sleep, and can increase the morbidity of the dental diseases.

关 键 词：nasopharyngeal carcinoma RADIOTHERAPY XEROSTOMIA 

分 类 号：R739.63[医药卫生—肿瘤]