女性生殖系统恶性肿瘤组织胞浆雌激素及孕激素受体的研究  

Study on cytosol estrogen and Progesteronereceptors in female genital system malignanttumors

作　　者：韩守威[1] 何斌[1] 唐茜萍[1] 刘珊玲[1] 彭芝兰[1] 曹泽毅[1] 

机构地区：[1]华西医科大学附属第二医院妇产科

出　　处：《中华妇产科杂志》1994年第1期12-15,共4页Chinese Journal of Obstetrics and Gynecology

基　　金：国家自然科学基金

摘　　要：应用葡聚糖－活性炭单点饱和分析法测定３４４例子宫内膜癌，１７７例子宫颈癌，２８９例卵巢恶性肿瘤，１０例外阴癌及４例输卵管癌组织胞浆的雌激素受体（ＥＲ）和孕激素受体（ＰＲ）含量。结果：ＬＲ及ＰＲ均量从高到低均依次为子宫内膜癌，卵巢恶性肿瘤及子宫颈癌。并探讨生殖系统不同恶性肿瘤组织胞浆ＥＲ和ＰＲ阳性率与患者绝经前后、肿瘤分化程度、临床期别及其预后之间的关系。提示：ＥＲ和ＰＲ含量对指导肿瘤患者术后内分泌治疗及判断预后有一定价值。pecimens from 344 cases of endometrialcarcinoma, 289 cases of ovarian careinoma, 177 casesof cervical carcinoma, 10 vulva and 4 fallopian tubecareinoma were assayed for cytosol estrogen andprogesterone receptor (ER, PR) contents withdextran-coated charcoal (DCC) method. Positiverates of ER and PR in these malignant tumors in rela-tion to menstrual cycle, histological differentiation.clinical stage and prognosis of disease were studied.The results suggested that the contents of ER and PRmay play a role in guilding endocrine therapy andprognosis in the postoperative period. Further studyon vulvar and fallopian tube carcinomas should beundertaken.

关 键 词：生殖器肿瘤 女性 激素类 受体 

分 类 号：R737.303[医药卫生—肿瘤]