肺癌淋巴结转移的CT表现与细胞核仁组成区关系  

The Correlation Between CT Features and Cell Nucleolus Organizer Region of lymph Nodes Metastasis of lung Cancer

作　　者：刘勇[1] 魏江平[1] 路名芝[1] 李启明[1] 王夷黎[1] 陈大贤[1] 

机构地区：[1]江西省人民医院,南昌市330006

出　　处：《医学影像学杂志》1998年第1期34-36,共3页Journal of Medical Imaging

摘　　要：目的：探讨肺癌淋巴结转移CT表现与细胞核仁组成区的关系，以及CT扫描和AgNOR技术联合诊断肺癌纵隔淋巴结转移的可行性。材料与方法：应用CT扫描和AgNOR技术对38例肺癌淋巴结转移情况进行分析。结果：CT扫描淋巴结短径≥8mm的10例肺癌中淋巴结转移7例，此7例肺癌细胞的AgNOR／核均数为8.97±0．72。且AgNOR颗粒均表现为聚集型。伴淋巴结转移肺癌的AgNOR／核均数显著高于无淋巴结转移肺癌（P＜0．05）。结论：提示以CT扫描淋巴结短径≥8mm，肺癌细胞核内AgNOR颗粒为聚集型，AgNOR／核均数≥8作为标准诊断肺癌淋巴结转移有较高的特异性及敏感性。AgNOR技术及CT扫描联合诊断肺癌淋巴结转移有较好的临床应用前景。Purpose: To study the correlation betwween CT features and cell nucleolusd organizer region oflymph nodes metastasis of lung cancer. To investigate the possibility about the diagnosis of mediastinal lymphnodes metastasis of lung cancer by CT combine with AgNOR technology. Materials and Methods: By using CTcombine with AgNOR technology, lymph nodes metastasis of 38 cases lung cancer was evaluated,Results:Thereare lymph nodes metastasis of 7 cases lung cancer in 10 cases lung cancer of the short axix diameter of nodes at CTshould be 8mm or larger. the mean numbers of AgNOR are 8. 97±0. 72 and distribution of lymph nodes metastasisThe mean numbers of AgNOR in lung cancer cell of lymph nodes metastasis is higher than lymph nodes nonmetastasis (P<0.05). Conclusion:The suggest that size thresholds were established for the diagnosis of mediastinallymph nodes metastasis of lung cancer:the short axix diameter of nodes at CT should be 8mm or larger and themean numbers of AgNOR should be 8 or higher,distribution of AgN ORbe collection type.

关 键 词：细胞核仁组成区 CT表现 AGNOR技术 AgNOR颗粒 纵隔淋巴结转移 CT扫描 无淋巴结转移 临床应用前景 联合诊断 肺癌细胞 标准诊断 细胞核内 敏感性 特异性 均数 聚集 

分 类 号：R733.72[医药卫生—肿瘤] R734.2[医药卫生—临床医学]