多巴胺D_3受体配体的研究和应用  

Study and Application of D_3 Receptor Ligand

作　　者：顾莉洁[1] 蔡进[2] 李铭东[1] 张姣月[1] 吉民[1] 

机构地区：[1]东南大学化学化工系 [2]中国药科大学新药研究中心,江苏南京210009

出　　处：《药学进展》2005年第5期218-221,共4页Progress in Pharmaceutical Sciences

摘　　要：综述有潜在治疗价值的多巴胺D3受体配体如多巴胺D3受体激动剂、部分激动剂和多巴胺D3受体拮抗剂的研究和应用近况。多巴胺D3受体与帕金森病、精神分裂症等神经性或精神性疾病及药物成瘾等有关。Some D_ 3 receptor ligands with potential medical value, involving D_ 3 receptor agonists, partial agonists and D_ 3 receptor antagonists were reviewed. D_ 3 receptor is related to many kinds of nervous or psychical disease, such as Parkinsonism and Schizophrenia, and is also related to the drug addiction.

关 键 词：多巴胺D3受体 多巴胺D3受体配体 部分激动剂 拮抗剂 

分 类 号：R971[医药卫生—药品]