膳食胡萝卜素对肺癌发病危险的影响  

A Matched Case-Control Study on the Relations between Beta Carotene and Lung Cancer

作　　者：谭爱军[1] 何尚浦[1] 黄铭西[1] 李国光[1] 龚兰英 郭有峰 

机构地区：[1]同济医科大学流行病学教研室

出　　处：《中华流行病学杂志》1995年第4期199-202,共4页Chinese Journal of Epidemiology

摘　　要：通过１５６对１：１配比病例对照研究，分析了武汉地区肺癌患者及其一般疾病住院对照的膳食主要营养素摄入情况。结果表明，病例组膳食胡萝卜素、维生素Ｃ、纤维素摄入水平显著低于对照。作者还分析了膳食胡萝卜素摄入量与肺癌各病理类型发病危险的关系，按吸烟因素分层进行ＯＲ趋势检验，发现膳食胡萝卜素水平与肺腺癌病理类型的ＯＲ趋势无统计显著性差异，但与肺鳞癌及其它肺癌病理类型发病存在暴露剂量－反应关系。n order to discover the relationship between dietary nutrients intake and risk of lung cancer 1:1 matched case control study on 156 recent histologiclly diagnosed primary lung cancer patients and 156 patients with respiratory tumour and other related diseases as controls,was conducted in Wuhan;All cases and controls were asked to participate in the nutritional assessment program and a food frequency questionaire containing 64 food items was filled in. The findings showed that there was a statistically significant difference between dietary intake of beta carotene between the two groups(2877.13±393.43 vs. 3445±430.98μ g/day).Having controled the confounding factor of cigarette smoking,a significant linear trend for lower dietary carotene intake toward higher lung cancer risk was observed.

关 键 词：肺肿瘤 胡萝卜素 膳食 

分 类 号：R734.2[医药卫生—肿瘤]