脂质沉积性肌病2例──治疗前后电镜观察  

Lipids Storage Myopathy:Electron Microscopic Observation before and after Treatment

作　　者：张平[1] 陈诒[1] 陈伟贤[1] 

机构地区：[1]南京医科大学附属脑科医院,南京医科大学附一院神经科

出　　处：《电子显微学报》1995年第5期336-340,共5页Journal of Chinese Electron Microscopy Society

摘　　要：应用电子显微镜对两例脂质沉积性肌病肌活检标本进行超微形态学观察。治疗前光镜下见肌纤维内油红Ｏ、苏丹黑Ｂ均呈阳性反应的脂质颗粒，电镜下表现为肌原纤维间及肌膜下平行串珠状或成簇排列的无膜脂肪空泡，其大小较为一致。患者经强的松及核黄素治疗，两周后复查肌活检，光镜下显示正常，电镜下脂肪空泡全部或大部消失，原来被脂肪空泡占据的部分仅留下小片糖元和无定型物质填充。Muscle biopsies in 2 patients with lipid storage myopathy are reported.Before treatment,EM. showed thatlipid droplets,nonmembrane bound,accumulated between myofibrils in parallel rows and in the subsarcolemmalregion. Following treatment.Lipid droplets may disappear and be left with some glycogen and infinite form ma-terials in these regions.

关 键 词：肌活检 脂质沉积性肌病 电镜检查 

分 类 号：R746[医药卫生—神经病学与精神病学] R741.044[医药卫生—临床医学]