绿茶清除羟自由基作用的实验研究  

EFFECT OF THE GREEN TEA EXTRACT ON THE CLEAR AWAY HYDROXYL RADICAL BY ESR

作　　者：罗素琼[1] 刘学泽[1] 贺海鹰[1] 

机构地区：[1]华西医科大学劳动卫生教研究室,华中理工大学化学系

出　　处：《现代预防医学》1995年第1期48-50,共3页Modern Preventive Medicine

基　　金：高校博士点基金;CMB基金

摘　　要：在Ｆｅ２＋－ＥＤＴＡ和Ｈ２Ｏ２发生羟自由基（ＯＨ·）的模拟体系中，用电子顺磁共振谱仪（ＥＳＲ）观察了绿茶水溶液对ＯＨ·的清除效果，结果显示，ＥＳＲ的ＯＨ·峰强随茶汁浓度的增加而减弱，在２５ｍｌ水溶液中绿茶为１、５、１０ｇ时，对ＯＨ·的清除率分别为１７．９％、５０．５％、８５．６％。The formation of the hydroxyl radical (OH) may occur directly through the Fenton reaction that Fe2++H2O2→OH.By means of trapping agent DMPO, a typical curve of OH. signal was abserved by electron spin resonance (ESR). After addition green tea extract, OH.signal reduced with increasing doses of green tea. The results showed that green tea may have effect of the clear away OH.

关 键 词：绿茶 羟自由基 抑癌作用 肿瘤 预防 

分 类 号：R730.1[医药卫生—肿瘤] TS272.51[医药卫生—临床医学]