加硒食盐对疾病的干预效果观察  

The role selenium salt on disease prevention

作　　者：郭春华 王明荣 刘圣贤 周本正 于树玉[1] 诸亚君[1] 

机构地区：[1]江苏省扬中市卫生局,江苏省扬中市卫生防疫站,中国医学科学院肿瘤研究所

出　　处：《微量元素与健康研究》1996年第1期42-44,共3页Studies of Trace Elements and Health

摘　　要：报告添加１５×ｌ０￣（－６）亚硒酸钠的富硒食盐对扬中居民主要疾病的５年干预效果（１９８９～１９９３年）。吃硒盐的５个乡镇１２．６万人，吃普通盐的５个乡镇１０．４万人，试验开始前成人血硒值０．０７２±０．０２μｇ／ｍｌ，观察结束时普盐区血硒０．０８５６±０．０１７μｇ／ｍｌ，硒盐区为０．０９２±０．０１３５μｇ／ｍｌ。普盐区１９８７～１９８８年总死亡率为８２５．３９×１０￣（－５），１９９０～１９９３年为８２０．５０×１０￣（－５），硒盐区则从７４９．８５×１０￣（－５）降为７０６．１５×１０￣（－５）下降了４３．７×１０￣（－５）或５．８３％。其中恶性肿瘤后４年比前２年下降３×１０￣（－５）或１２％，有统计意义，而对照区前后变化不大。主要呼吸系病（肺炎、支气管炎、肺气肿、哮喘）和３种心脏病（高血压性心脏病、急性心肌梗塞、冠心病）死亡率，硒盐区皆有下降而对照区均呈上升但未达显著性水平。The authors observed the role of l5 × 10-6 sodium selenite on disease prevention during l989-93 in Yangzhong Coun-ty,Jiangsu Province where the trace element Se is poor and the digestive cancer mortality has been very high.The treatment group(TG)consisted of l26000 pcrsons taking Se table salt.The control group(CG)consisted of l04000 persons who took ordinary saltwithout selenite. The concentration of blood Se of the population was 0.072±0.022μg/ml before the trial.After five years,theblood concentratiOn of Se were 0.0962±0.0I35μg/mland 0.0856±0.0l7μg/ml in TG and CG respectivelty.The overall mortalityrate per l00000 were 749.85 during l987-1988 and 706.15 durlng l990-1993 in TG,declining 5.83%。Especially in nialignanttumor,the niortality declined l2%,which was of statistical signlficance. But the overall niortality and cancer mortality were botheven in CG. Moreover we can see some declining treng of main respiratory diseases(pneunlonitis,bronchitis,emphysema,asthma)and three heart diseases(hypcrtention heart disease,acute myocardial infaction and other coronary heart disease)in TG rather thanIn CG though the statistical test was not significant.

关 键 词：硒 肝炎 恶性肿瘤 疾病 硒盐 

分 类 号：TS365[轻工技术与工程] Q581[生物学—生物化学]