2-甲基-1,3-二硫环庚烷的合成及香气研究  

Study on the synthesis of 2-methyl-1,3-dithiocycloheptane and odour

作　　者：胡卫兵[1] 刘红霞[1] 余爱农[1] 向必坤[1] 

机构地区：[1]湖北民族学院化学与环境工程学院,湖北恩施445000

出　　处：《中国调味品》2005年第12期23-26,共4页China Condiment

基　　金：国家民委重点科研项目(200145);湖北省教育厅重点项目(2003A007)

摘　　要：以硫代硫酸钠、1,4-二氯丁烷和乙醛为原料,用Bunte Salts法,经过一步操作合成了2-甲基-1,3-二硫环庚烷,其收率为42%。实验表明,当1,4-二氯丁烷与硫代硫酸钠以等摩尔投料时,可减少盐酸用量,并能避免单质硫的析出而影响分离提纯。用IR1、HNMR、MS证实了目标化合物结构,并对2-甲基-1,3-二硫环庚烷的香气进行了鉴定,结果表明2-甲基-1,3-二硫环庚烷具有浓郁的葱蒜气味,其阈值在水中为0.19ppm,在植物油中为12.90ppm。2-methyl-1,3-dithiocycloheptane were prepared through the aldehyde with Bunte＇s Salts prepared from 1,4-dichlorobutane and sodium thiosulfate. The yield of 2-methyl-1,3-dithiocycloheptane is 42%. The period of reaction is about 15h. The optimum molar ratio of 1,4-dichlorobutane and sodium thiosulfate was 1 ： 1. The structure of 2-methyl-1, 3-dithiocycloheptane were characterized by IR, 1HNMR,MS. The odour of 2-methyl-1,3- dithiocycloheptane was identified , the result showed that it＇s odour is intense onion and garlic fragrance.. The threshold of 1,3-dithiocycloheptane is 0. 19 ppm in water and 12.90 ppm in vegetable oil.

关 键 词：Bunte Salts法 合成 2-甲基-1 3-二硫环庚烷 香气 

分 类 号：O624.7[理学—有机化学] TQ651.1[理学—化学]