尾状核、豆状核和丘脑的三维可视化及与磁共振图像的融合  

RECONSTRUCTION AND FUSION WITH MRI OF CAUDATE NUCLEUS, LENTIFORM NUCLEUS AND THALAMUS

作　　者：李林[1] 刘翌勋[1] 宋志坚[1] 

机构地区：[1]复旦大学数字医学研究中心,上海200032

出　　处：《解剖学报》2005年第6期642-645,共4页Acta Anatomica Sinica

基　　金：国家自然科学基金资助项目(30370417)

摘　　要：目的依据中国虚拟人数据集对尾状核、豆状核和丘脑进行三维重建并与临床影像数据进行融合,为神经外科疾病的诊断与治疗提供形态学依据。方法以中国虚拟人数据集为依据,采用图像透明的方法对尾状核、豆状核和丘脑进行手工分割,在平滑处理中运用了腐蚀与膨胀的方法,并把分割后的神经结构与病人磁共振图像进行融合,最后用表面绘制与体绘制相结合的方法进行三维重建。结果重建后的图像可清晰显示尾状核、豆状核、丘脑各个神经结构的形态、位置和毗邻关系。可在三维空间中绕任意轴旋转任意角度,从不同的方向进行观察。融合后的图像能同时显示虚拟结构与病人MRI图像。结论用三维可视化与MRI图像融合方法获得的图像资料,对于解剖学的教学研究以及神经外科疾病的诊断与治疗具有重要的参考价值。Objective To reconstruct caudate nucleus, lentiform nucleus and thalamus three-dimensionally, fuse these neural structures with patient＇s radiological images and provide anatomical data for diagnosis and treatment of neurosurgical diseases. Methods Chinese Virtual Human dataset was segmented using image-transparency method at first and each image was smoothed by eroding and dilating, then fused neural structures with MRI, the neural structures and brain in MRI were reconstructed and displayed using surface rendering and volume rendering lastly. Results The reconstructed neural structures were smooth, natural and realistic. Their shapes and positions was clearly displayed and could be rotated, observed in any direction. On the fused images, the neural structures and tumor could be seen at the same time. Conclusion The reconstructed structures and fused images have great reference value to teaching and learning and diagnosis and treatment of neurosurgical diseases.

关 键 词：尾状核 豆状核 丘脑 配准 融合 三维重建 人 

分 类 号：R322.1[医药卫生—人体解剖和组织胚胎学]